The PHQ-PD as a screening tool for panic disorder in the primary care setting in Spain
Muñoz-Navarro, Roger (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Cano Vindel, Antonio (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Mae Wood, Cristina (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Ruíz Rodríguez, Paloma (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Medrano, Leonardo Adrián (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Limonero García, Joaquim T. (Joaquim Timoteo) (Universitat Autònoma de Barcelona)
Gracia Gracia, Irene (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Dongil Collado, Esperanza (Universidad Complutense de Madrid. Grupo de Investigación PsicAP)
Iruarrizaga, Itziar (Universidad Complutense de Madrid)

Data:	2016
Resum:	Introduction: Panic disorder is a common anxiety disorder and is highly prevalent in Spanish primary care centres. The use of validated tools can improve the detection of panic disorder in primary care populations, thus enabling referral for specialized treatment. The aim of this study is to determine the accuracy of the Patient Health Questionnaire-Panic Disorder (PHQ-PD) as a screening and diagnostic tool for panic disorder in Spanish primary care centres. Method: We compared the psychometric properties of the PHQ-PD to the reference standard, the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) interview. General practitioners referred 178 patients who completed the entire PHQ test, including the PHQ-PD, to undergo the SCID-I. The sensitivity, specificity, positive and negative predictive values and positive and negative likelihood ratios of the PHQ-PD were assessed. Results: The operating characteristics of the PHQ-PD are moderate. The best cut-off score was 5 (sensitivity . 77, specificity . 72). Modifications to the questionnaire's algorithms improved test characteristics (sensitivity . 77, specificity . 72) compared to the original algorithm. The screening question alone yielded the highest sensitivity score (. 83). Conclusion: Although the modified algorithm of the PHQ-PD only yielded moderate results as a diagnostic test for panic disorder, it was better than the original. Using only the first question of the PHQ-PD showed the best psychometric properties (sensitivity). Based on these findings, we suggest the use of the screening questions for screening purposes and the modified algorithm for diagnostic purposes.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	PloS one, Vol. 11, No. 8 (2016) , p. e0161145, ISSN 1932-6203

DOI: 10.1371/journal.pone.0161145
PMID: 27525977

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