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Auxin influx carriers control vascular patterning and Xylem differentiation in Arabidopsis thaliana
Fábregas, Norma (Centre de Recerca en Agrigenòmica)
Formosa Jordan, Pau (Universitat de Barcelona. Departament d'Estructura i Constituents de la Matèria)
Confraria, Ana (Centre de Recerca en Agrigenòmica)
Siligato, Riccardo (Helsingin yliopisto. Biotekniikan instituutti)
Alonso, Jose M. (North Carolina State University. Department of Plant and Microbial Biology)
Swarup, Ranjan (The University of Nottingham. Centre for Plant Integrative Biology)
Bennett, Malcolm J. (The University of Nottingham. Centre for Plant Integrative Biology)
Mähönen, Ari Pekka (Helsingin yliopisto. Biotekniikan instituutti)
Caño Delgado, Ana I. (Centre de Recerca en Agrigenòmica)
Ibañes, Marta (Universitat de Barcelona. Departament d'Estructura i Constituents de la Matèria)

Date: 2015
Abstract: Auxin is an essential hormone for plant growth and development. Auxin influx carriers AUX1/LAX transport auxin into the cell, while auxin efflux carriers PIN pump it out of the cell. It is well established that efflux carriers play an important role in the shoot vascular patterning, yet the contribution of influx carriers to the shoot vasculature remains unknown. Here, we combined theoretical and experimental approaches to decipher the role of auxin influx carriers in the patterning and differentiation of vascular tissues in the Arabidopsis in- florescence stem. Our theoretical analysis predicts that influx carriers facilitate periodic patterning and modulate the periodicity of auxin maxima. In agreement, we observed fewer and more spaced vascular bundles in quadruple mutants plants of the auxin influx carriers aux1lax1lax2lax3. Furthermore, we show AUX1/LAX carriers promote xylem differentiation in both the shoot and the root tissues. Influx carriers increase cytoplasmic auxin signaling, and thereby differentiation. In addition to this cytoplasmic role of auxin, our computational simulations propose a role for extracellular auxin as an inhibitor ofxylem differentiation. Al-together, our study shows that auxin influx carriers AUX1/LAX regulate vascular patterning and differentiation in plants.
Note: Número d'acord de subvenció MEC/FPU/AP2008/03325
Note: Número d'acord de subvenció MICINN/FIS2012-37655-C02-02
Note: Número d'acord de subvenció MICINN/FIS2009-13360-C03-01
Note: Número d'acord de subvenció MICINN/BIO2013/43873
Note: Número d'acord de subvenció MICINN/BI02010/16673
Note: Número d'acord de subvenció AGAUR/2014/SGR-878
Note: Número d'acord de subvenció AGAUR/2009/SGR-0014
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès.
Document: article ; recerca ; publishedVersion
Published in: Plos genetics, Vol. 11, issue 4 (April 2015) , e1005183, ISSN 1553-7404

DOI: 10.1371/journal.pgen.1005183
PMID: 25922946


26 p, 11.7 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (scientific output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
Articles > Published articles

 Record created 2017-07-11, last modified 2018-10-21



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