A genome-wide perspective about the diversity and demographic history of seven Spanish goat breeds
Manunza, Arianna (Centre de Recerca en Agrigenòmica)
Noce, Antonia (Centre de Recerca en Agrigenòmica)
Serradilla Manrique, Juan Manuel (Universidad de Córdoba. Departamento de Genética)
Goyache Goñi, Félix María (SERIDA-Deva. Área de Genética y Reproducción Animal)
Martinez, Amparo (Universidad de Córdoba. Departamento de Genética)
Capote, Juan (Instituto Canario de Investigaciones Agrarias)
Delgado Bermejo, Juan Vicente (Universidad de Córdoba. Departamento de Genética)
Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Patologia i de Producció Animals)
Muñoz, Eva (Universidad de Córdoba. Departamento de Genética)
Molina, Antonio (Universidad de Córdoba. Departamento de Genética)
Landi, Vincenzo (Universidad de Córdoba. Departamento de Genética)
Pons Barro, Agueda (Servei de Millora Agrària i Pesquera (SEMILLA). Unitat de Races Autòctones)
Bâlteanu, Valentin Adrian (University of Agricultural Sciences and Veterinary Medicine (Cluj-Napoca, Romania))
Traoré, Amadou (Institut de l'Environnement et Recherches Agricoles (Burkina Faso))
Vidilla Gil, Montserrat (Associació de Ramaders de Cabra Blanca de Rasquera)
Sánchez-Rodríguez, Manuel (Universidad de Córdoba. Departamento de Genética)
Sánchez Bonastre, Armando (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Cardoso, Tainã Figueiredo (Centre de Recerca en Agrigenòmica)
Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)

Date:	2016
Abstract:	Background: The main goal of the current work was to infer the demographic history of seven Spanish goat breeds (Malagueña, Murciano-Granadina, Florida, Palmera, Mallorquina, Bermeya and Blanca de Rasquera) based on genomewide diversity data generated with the Illumina Goat SNP50 BeadChip (population size, N = 176). Five additional populations from Europe (Saanen and Carpathian) and Africa (Tunisian, Djallonké and Sahel) were also included in this analysis (N = 80) for comparative purposes. Results: Our results show that the genetic background of Spanish goats traces back mainly to European breeds although signs of North African admixture were detected in two Andalusian breeds (Malagueña and MurcianoGranadina). In general, observed and expected heterozygosities were quite similar across the seven Spanish goat breeds under analysis irrespective of their population size and conservation status. For the Mallorquina and Blanca de Rasquera breeds, which have suffered strong population declines during the past decades, we observed increased frequencies of large-sized (ROH), a finding that is consistent with recent inbreeding. In contrast, a substantial part of the genome of the Palmera goat breed comprised short ROH, which suggests a strong and ancient founder effect. Conclusions: Admixture with African goats, genetic drift and inbreeding have had different effects across the seven Spanish goat breeds analysed in the current work. This has generated distinct patterns of genome-wide diversity that provide new clues about the demographic history of these populations.
Grants:	Ministerio de Economía y Competitividad SEV-20150533 Ministerio de Economía y Competitividad RTA 2011-00108-C02-02
Note:	Altres ajuts: Félix Goyache is supported by Grant FICYT GRUPIN14-113. Valentin Balteanu is the recipient of a grant awarded under the frame of the European Social Fund, Human Resources Development Operational Program 2007-2013, Project No. POSDRU/159/1.5/S/132765.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	Genetics, selection, evolution, Vol. 48 (2016) , art. 52, ISSN 1297-9686

DOI: 10.1186/s12711-016-0229-6
PMID: 27455838

9 p, 2.0 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
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