The effect of single recombination events on coalescent tree height and shape
Ferretti, Luca (Universität zu Köln. Institut für Genetik)
Disanto, Filippo (Universität zu Köln. Institut für Genetik)
Wiehe, Thomas (Centre de Recerca en Agrigenòmica)

Date:	2013
Abstract:	The coalescent with recombination is a fundamental model to describe the genealogical history of DNA sequence samples from recombining organisms. Considering recombination as a process which acts along genomes and which creates sequence segments with shared ancestry, we study the influence of single recombination events upon tree characteristics of the coalescent. We focus on properties such as tree height and tree balance and quantify analytically the changes in these quantities incurred by recombination in terms of probability distributions. We find that changes in tree topology are often relatively mild under conditions of neutral evolution, while changes in tree height are on average quite large. Our results add to a quantitative understanding of the spatial coalescent and provide the neutral reference to which the impact by other evolutionary scenarios, for instance tree distortion by selective sweeps, can be compared.
Grants:	Ministerio de Ciencia e Innovación AGL2010-14822 Ministerio de Ciencia e Innovación CSD2007-00036
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	PloS one, Vol. 8, issue 4 (April 2013) , e60123, ISSN 1932-6203

DOI: 10.1371/journal.pone.0060123
PMID: 23593168

15 p, 893.5 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
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