Acute-Onset Endophthalmitis Caused by Alloiococcus otitidis following a Dexamethasone Intravitreal Implant
Marchino, Tizana (Institut d'Investigació Biomèdica Sant Pau)
Vela, José I. (Institut Comtal d'Oftalmologia)
Bassaganyas Vilarrasa, Francisca (Institut d'Investigació Biomèdica Sant Pau)
Sánchez, Saskia (Institut d'Investigació Biomèdica Sant Pau)
Buil Calvo, José Antonio (Universitat Autònoma de Barcelona. Departament de Cirurgia)
Universitat Autònoma de Barcelona

Date:	2013
Abstract:	To report the first case of acute endophthalmitis caused by Alloiococcus otitidis after a dexamethasone intravitreal implant. A 74-year-old female was treated with intravitreal Ozurdex ® in her left eye for central retinal vein occlusion (CRVO). Best-corrected visual acuity (BCVA) in the eye was 4/20. Intravitreal injection was uneventful. At 48 h after injection, she developed ocular pain and visual acuity had dropped to light perception. Endophthalmitis associated with intravitreal injection was suspected. The patient did not show a favorable clinical response following systemic, intravitreal, and topical fortified antibiotics. We then performed a vitreous biopsy and removed the Ozurdex implant by pars plana vitrectomy. A vitreous culture was positive for A. otitidis. At the 2-month follow up, no inflammation was observed, but due to CRVO and probably aggravated by endophthalmitis, the fundus showed macular fibrosis. The final BCVA was finger counting at 30 cm in her left eye. In cases of an intravitreal implant associated with endophthalmitis, we recommend removal of the device because it may act as a permanent reservoir of organisms if it remains in the vitreous cavity.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Alloiococcus otitidis ; Dexamethasone implant ; Endophthalmitis ; Ozurdex
Published in:	Case Reports in Ophthalmology, Vol. 4 (march 2013) , p. 37-41, ISSN 1663-2699

DOI: 10.1159/000348809
PMID: 23626572

5 p, 679.8 KB

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