Management of a caseous lymphadenitis outbreak in a new Iberian ibex (Capra pyrenaica) stock reservoir
Colom Cadena, Andreu (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Velarde, Roser (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Salinas, Jesús
Borge, Carmen
García-Bocanegra, Ignacio
Serrano Ferron, Emmanuel (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Gassó, Diana (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Bach i Raich, Ester (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Casas Díaz, Encarna (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
López Olvera, Jorge R. (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Lavín González, Santiago (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
León-Vizcaíno, Luís
Mentaberre García, Gregorio (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)

Data:	2014
Resum:	In 2010, an Iberian ibex (Capra pyrenaica hispanica) stock reservoir was established for conservation purposes in north-eastern Spain. Eighteen ibexes were captured in the wild and housed in a 17 hectare enclosure. Once in captivity, a caseous lymphadenitis (CLA) outbreak occurred and ibex handlings were carried out at six-month intervals between 2010 and 2013 to perform health examinations and sampling. Treatment with a bacterin-based autovaccine and penicillin G benzatine was added during the third and subsequent handlings, when infection by Corynebacterium pseudotuberculosis was confirmed. Changes in lesion score, serum anti- C. pseudotuberculosis antibodies and haematological parameters were analyzed to assess captivity effects, disease emergence and treatment efficacy. Serum acute phase proteins (APP) Haptoglobin (Hp), Amyloid A (SAA) and Acid Soluble Glycoprotein (ASG) concentrations were also determined to evaluate their usefulness as indicators of clinical status. Once in captivity, 12 out of 14 ibexes (85. 7%) seroconverted, preceding the emergence of clinical signs; moreover, TP, WBC, eosinophil and platelet cell counts increased while monocyte and basophil cell counts decreased. After treatment, casualties and fistulas disappeared and both packed cell volume (PCV) and haemoglobin concentration significantly increased. Hp, SAA and ASG values were under the limit of detection or showed no significant differences. A role for captivity in contagion rate is suggested by the increase in antibody levels against C. pseudotuberculosis and the emergence of clinical signs. Although boosted by captivity, this is the first report of an outbreak of caseous lymphadenitis displaying high morbidity and mortality in wild ungulates. Treatment consisting of both vaccination and antibiotic therapy seemed to prevent mortality and alleviate disease severity, but was not reflected in the humoural response. Haematology and APP were not useful indicators in our study, perhaps due to the sampling frequency. Presumably endemic and irrelevant in the wild, this common disease of domestic small ruminants is complicating conservation efforts for the Iberian ibex in north-eastern Spain.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Capra pyrenaica ; Corynebacterium pseudotuberculosis ; Caseous lymphadenitis ; Antibodies ; Autovaccine ; Acute phase proteins
Publicat a:	Acta Veterinaria Scandinavica, Vol. 56 (december 2014) , ISSN 1751-0147

DOI: 10.1186/s13028-014-0083-x
PMID: 25492129

11 p, 487.4 KB

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