Deep Sclerectomy With a New Nonabsorbable Uveoscleral Implant (Esnoper-Clip) : 1-Year Outcomes
Loscos Arenas, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Parera-Arranz, Angels (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Romera Romero, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Castellvi-Manent, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Sabala-Llopart, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
de la Cámara-Hermoso, Julio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Universitat Autònoma de Barcelona

Date:	2015
Abstract:	To report the safety and the effectiveness of deep sclerectomy (DS) with a new nonabsorbable uveoscleral hema implant (Esnoper-Clip) designed to increase trabecular and uveoscleral outflow and to achieve higher intrascleral blebs. Twenty-seven eyes of 27 patients with open-angle glaucoma, who underwent DS with an Esnoper-Clip implant, were included in this study. All patients were followed up after 12 months. A significant decrease in intraocular pressure was observed after surgery, changing from a preoperative mean of 26. 6±5. 2 mm Hg to a postoperative mean of 15. 3±5 mm Hg (P <0. 001) at 12 months. There was also a significant reduction in the number of glaucoma drugs needed, varying from 2. 5 per patient to 0. 3 (P <0. 001) 1 year after surgery. The main intrascleral lake height and volume at 12 months was 0. 7±0. 1 mm and 3. 9±1. 3 mm 3, respectively. No intraoperative complications occurred. The main postoperative complications were a positive Seidel test result at 24 hours in 2 eyes (7. 4%), hyphema in 2 eyes (7. 4%), and choroidal detachment in 1 eye (3. 7%). All these complications resolved successfully. The need for additional mitomycin-C injections was recorded in 4 eyes (14. 8%), twice in 2 of them. Twelve eyes (44. 4%) underwent postsurgical Nd:YAG laser goniopuncture with a mean time between surgery and this procedure of 4. 3 months. Mean intraocular pressure after Nd:YAG laser goniopuncture decreased from 19. 2 to 15. 5 mm Hg (P <0. 001). DS with an uveoscleral hema implant (Esnoper-Clip) is a safe and effective technique for the management of open-angle glaucoma.
Note:	Altres ajuts: AJL Ophthalmics supports the Health Sciences Research Institute "Germans Trias i Pujol" Foundation.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Deep sclerectomy ; Open-angle glaucoma ; Esnoper-Clip
Published in:	Journal of Glaucoma, Vol. 24 (august 2015) , p. 421-425, ISSN 1536-481X

DOI: 10.1097/IJG.0000000000000253
PMID: 25836660

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles