What pulmonologists think about the asthma-COPD overlap syndrome
Miravitlles, Marc (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
Alcázar-Navarrete, Bernardino (Respiratory Department, Hospital de Alta Resolucion de Loja)
Alvarez Gutiérrez, Francisco Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia))
Bazús González, Teresa (Hospital Universitario Central de Asturias)
Calle Rubio, Myriam (Hospital Clínico San Carlos (Madrid))
Casanova, Ciro (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife))
Cisneros, Carolina (Instituto de Investigación Hospital Universitario de la Princesa)
De Torres, Juan Pablo (Clínica Universidad de Navarra)
Entrenas, Luis M. (Hospital Universitario Reina Sofía (Còrdova, Espanya))
Esteban, Cristóbal (Hospital de Galdakao (Usansolo, Biscaia))
García-Sidro, Patricia (Hospital Universitario de La Plana, Vila-real)
Cosio, Borja G.. (Institut d'Investigació Sanitària de Palma)
Huerta, Arturo (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Iriberri, Milagros (Hospital Universitario de Cruces (Barakaldo, País Basc))
Izquierdo, José Luis (Hospital Universitario de Guadalajara)
López Viña, Antolín (Hospital Universitario Puerta de Hierro Majadahonda (Madrid))
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia))
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València))
Pérez de Llano, Luis (Hospital Universitario Lucus Augusti (Lugo))
Perpiñá, Miguel (Hospital Universitari i Politècnic La Fe (València))
Ros, José Antonio (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia))
Serrano, José (Hospital Comarcal de Inca)
Soler-Cataluña, Juan José (Hospital Arnau de Vilanova (Lleida, Catalunya))
Torrego, Alfons (Institut d'Investigació Biomèdica Sant Pau)
Urrutia, Isabel (Hospital de Galdakao (Usansolo, Biscaia))
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona

Fecha:	2015
Resumen:	Some patients with COPD may share characteristics of asthma; this is the so-called asthma-COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population. We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS. A total of 26 pulmonologists with a mean age of 49. 7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84. 6% recognized the existence of ACOS and stated that a mean of 12. 6% of their patients might have this syndrome. In addition, 80. 8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88. 5%), significant smoking exposure (73. 1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity <0. 7 (69. 2%). The most accepted diagnostic criteria were eosinophilia in sputum (80. 8%), a very positive bronchodilator test (69. 2%), and a history of asthma before 40 years of age (65. 4%). Up to 96. 2% agreed that first-line treatment for ACOS was the combination of a long-acting β-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS. Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting β-agonist/inhaled corticosteroids.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Asthma ; COPD ; ACOS ; Survey ; Guidelines
Publicado en:	International journal of COPD, Vol. 10 (july 2015) , p. 1321-1330, ISSN 1178-2005

DOI: 10.2147/COPD.S88667
PMID: 25587219
PMID: 26270415

10 p, 374.7 KB

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