The MANGUA Project : A Population-Based HIV Cohort in Guatemala
García, Juan Ignacio (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)
Samayoa, Blanca (Clínica Familiar Luis Ángel García, San Juan de Dios Hospital, Asociación de Salud Integral, 1001 Guatemala City, Guatemala)
Sabidó Espin, Meritxell (Universitat de Girona. Departament de Ciències Mèdiques)
Prieto, Luis Alberto (Fundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital Technical Advisor Unit (UAT), Escuintla National Hospital)
Pinzón, Rodolfo (Roosevelt Hospital)
Santa Marina de León, Luis Roberto (Juan José Ortega de Coatepeque National Hospital)
Ortiz, José Fernando (Hospital del Instituto Guatemalteco de Seguridad Social (IGSS))
Ponce, Ernesto (National Programme for Prevention and Control of STI and HIV/AIDS (PNS))
Mejía Villatoro, Carlos Rodolfo (Roosevelt Hospital)
Arathoon, Eduardo (Clínica Familiar Luis Ángel García, San Juan de Dios Hospital, Asociación de Salud Integral)
Casabona-Barbarà, Jordi (Institut Català d'Oncologia)
Study Group, The Mangua Cohort (Fundació Sida i Societat, Technical Advisor Unit (UAT), Escuintla National Hospital)

Data:	2015
Resum:	Introduction. The MANGUA cohort is an ongoing multicenter, observational study of people living with HIV/AIDS in Guatemala. The cohort is based on the MANGUA application which is an electronic database to capture essential data from the medical records of HIV patients in care. Methods. The cohort enrolls HIV-positive adults ≥16 years of age. A predefined set of sociodemographic, behavioral, clinical, and laboratory data are registered at entry to the cohort study. Results. As of October 1st, 2012, 21 697 patients had been included in the MANGUA cohort (median age: 33 years, 40. 3% female). At enrollment 74. 1% had signs of advanced HIV infection and only 56. 3% had baseline CD4 cell counts. In the first 12 months after starting antiretroviral treatment 26. 9% (n = 3938) of the patients were lost to the program. Conclusions. The implementation of a cohort of HIV-positive patients in care in Guatemala is feasible and has provided national HIV indicators to monitor and evaluate the HIV epidemic. The identified percentages of late presenters and high rates of LTFU will help the Ministry to target their current efforts in improving access to diagnosis and care.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Publicat a:	AIDS Research and Treatment, Vol. 2015 (september 2015) , ISSN 2090-1259

DOI: 10.1155/2015/372816
PMID: 26425365

8 p, 1.0 MB

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