Web of Science: 3 citas, Scopus: 3 citas, Google Scholar: citas,
Coping with iron limitation : a metabolomic study of Synechocystis sp. PCC 6803
Rivas Ubach, Albert (Centre de Recerca Ecològica i Aplicacions Forestals)
Poret-Peterson, Amisha T. (Arizona State University. School of Earth and Space Exploration)
Peñuelas, Josep (Centre de Recerca Ecològica i Aplicacions Forestals)
Pérez Trujillo, Miriam (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear)
Legido-Quigley, Cristina (King’s College London. Institute of Pharmaceutical Science)
Oravec, Michal (Akademie věd České Republiky. Centrum výzkumu globální změny)
Urban, Otmar (Akademie věd České Republiky. Centrum výzkumu globální změny)
Elser, James J. (University of California. Crops Pathology and Genetics Research Unit)

Fecha: 2018
Resumen: Iron (Fe) is a key element for all living systems, especially for photosynthetic organisms because of its important role in the photosynthetic electron transport chain. Fe limitation in cyanobacteria leads to several physiological and morphological changes. However, the overall metabolic responses to Fe limitation are still poorly understood. In this study, we integrated elemental, stoichiometric, macromolecular, and metabolomic data to shed light on the responses of Synechocystis sp. PCC 6803, a non-N2-fixing freshwater cyanobacterium, to Fe limitation. Compared to Synechocystis growing at nutrient replete conditions, Fe-limited cultures had lower growth rates and amounts of chlorophyll a, RNA, RNA:DNA, C, N, and P, and higher ratios of protein:RNA, C:N, C:P, and N:P, in accordance with the growth rate hypothesis which predicts faster growing organisms will have decreased biomass RNA contents and C:P and N:P ratios. Fe-limited Synechocystis had lower amounts Fe, Mn, and Mo, and higher amount of Cu. Several changes in amino acids of cultures growing under Fe limitation suggest nitrogen limitation. In addition, we found substantial increases in stress-related metabolites in Fe-limited cyanobacteria such antioxidants. This study represents an advance in understanding the stoichiometric, macromolecular, and metabolic strategies that cyanobacteria use to cope with Fe limitation. This information, moreover, may further understanding of changes in cyanobacterial functions under scenarios of Fe limitation in aquatic ecosystems.
Nota: Número d'acord de subvenció EC/FP7/610028
Nota: Número d'acord de subvenció MINECO/CGL2013-48074-P
Nota: Número d'acord de subvenció AGAUR/2014/SGR-274
Derechos: Tots els drets reservats
Lengua: Anglès.
Documento: article ; recerca ; acceptedVersion
Materia: Metabolomics ; Metallomics ; Iron limitation ; Cyanobacteria ; Ecological stoichiometry
Publicado en: Acta physiologiae plantarum, Vol. 40, art. 28 (Feb. 2018) , ISSN 0137-5881

DOI: 10.1007/s11738-018-2603-1


Post-print
35 p, 1.8 MB

El registro aparece en las colecciones:
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias > CREAF (Centre de Recerca Ecològica i d'Aplicacions Forestals) > Imbalance-P
Artículos > Artículos de investigación
Artículos > Artículos publicados

 Registro creado el 2018-01-31, última modificación el 2019-04-08



   Favorit i Compartir