Scopus: 1 cites, Web of Science: 1 cites,
Coping with iron limitation : a metabolomic study of Synechocystis sp. PCC 6803
Rivas Ubach, Albert (Centre de Recerca Ecològica i Aplicacions Forestals)
Poret-Peterson, Amisha T. (Arizona State University. School of Earth and Space Exploration)
Peñuelas, Josep (Centre de Recerca Ecològica i Aplicacions Forestals)
Pérez-Trujillo, Miriam (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear)
Legido-Quigley, Cristina (King’s College London. Institute of Pharmaceutical Science)
Oravec, Michal (Akademie věd České Republiky. Centrum výzkumu globální změny)
Urban, Otmar (Akademie věd České Republiky. Centrum výzkumu globální změny)
Elser, James J. (University of California. Crops Pathology and Genetics Research Unit)

Data: 2018
Resum: Iron (Fe) is a key element for all living systems, especially for photosynthetic organisms because of its important role in the photosynthetic electron transport chain. Fe limitation in cyanobacteria leads to several physiological and morphological changes. However, the overall metabolic responses to Fe limitation are still poorly understood. In this study, we integrated elemental, stoichiometric, macromolecular, and metabolomic data to shed light on the responses of Synechocystis sp. PCC 6803, a non-N2-fixing freshwater cyanobacterium, to Fe limitation. Compared to Synechocystis growing at nutrient replete conditions, Fe-limited cultures had lower growth rates and amounts of chlorophyll a, RNA, RNA:DNA, C, N, and P, and higher ratios of protein:RNA, C:N, C:P, and N:P, in accordance with the growth rate hypothesis which predicts faster growing organisms will have decreased biomass RNA contents and C:P and N:P ratios. Fe-limited Synechocystis had lower amounts Fe, Mn, and Mo, and higher amount of Cu. Several changes in amino acids of cultures growing under Fe limitation suggest nitrogen limitation. In addition, we found substantial increases in stress-related metabolites in Fe-limited cyanobacteria such antioxidants. This study represents an advance in understanding the stoichiometric, macromolecular, and metabolic strategies that cyanobacteria use to cope with Fe limitation. This information, moreover, may further understanding of changes in cyanobacterial functions under scenarios of Fe limitation in aquatic ecosystems.
Nota: Número d'acord de subvenció EC/FP7/610028
Nota: Número d'acord de subvenció MINECO/CGL2013-48074-P
Nota: Número d'acord de subvenció AGAUR/2014/SGR-274
Drets: Tots els drets reservats
Llengua: Anglès.
Document: article ; recerca ; acceptedVersion
Matèria: Metabolomics ; Metallomics ; Iron limitation ; Cyanobacteria ; Ecological stoichiometry
Publicat a: Acta physiologiae plantarum, Vol. 40, art. 28 (Feb. 2018) , ISSN 0137-5881

DOI: 10.1007/s11738-018-2603-1


Disponible a partir de: 2019-02-30
Post-print

El registre apareix a les col·leccions:
Documents de recerca > Documents dels grups de recerca de la UAB > Centres i grups de recerca (producció científica) > Ciències > CREAF (Centre de Recerca Ecològica i d'Aplicacions Forestals) > Imbalance-P
Articles > Articles de recerca
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 Registre creat el 2018-01-31, darrera modificació el 2018-10-20



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