Web of Science: 6 citations, Scopus: 2 citations, Google Scholar: citations,
Individual Signatures Define Canine Skin Microbiota Composition and Variability
Cuscó, Anna (Vetgenomics)
Sánchez, Armand (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular)
Altet, Laura (Vetgenomics)
Ferrer, Lluís (Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University)
Francino, Olga (Universitat Autònoma de Barcelona. Servei Veterinari de Genètica Molecular)

Date: 2017
Abstract: Dogs present almost all their skin sites covered by hair, but canine skin disorders are more common in certain skin sites and breeds. The goal of our study is to characterize the composition and variability of the skin microbiota in healthy dogs and to evaluate the effect of the breed, the skin site, and the individual. We have analyzed eight skin sites of nine healthy dogs from three different breeds by massive sequencing of 16S rRNA gene V1–V2 hypervariable regions. The main phyla inhabiting the skin microbiota in healthy dogs are Proteobacteria, Firmicutes, Fusobacteria, Actinobacteria, and Bacteroidetes. Our results suggest that skin microbiota composition pattern is individual specific, with some dogs presenting an even representation of the main phyla and other dogs with only a major phylum. The individual is the main force driving skin microbiota composition and diversity rather than the skin site or the breed. The individual is explaining 45% of the distances among samples, whereas skin site explains 19% and breed 9%. Moreover, analysis of similarities suggests a strong dissimilarity among individuals (R = 0. 79, P = 0. 001) that is mainly explained by low-abundant species in each dog. Skin site also plays a role: inner pinna presents the highest diversity value, whereas perianal region presents the lowest one and the most differentiated microbiota composition.
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès.
Document: article ; recerca ; publishedVersion
Subject: Skin ; Microbiota ; Microbiome ; Dog ; Canine ; Coat ; Skin site ; 16S
Published in: Frontiers in Veterinary Science, Vol. 4 (february 2017) , ISSN 2297-1769

PMID: 28220148
DOI: 10.3389/fvets.2017.00006

12 p, 5.7 MB

The record appears in these collections:
Articles > Research articles
Articles > Published articles

 Record created 2018-02-08, last modified 2019-10-07

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