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Clinical Features, Imaging Characteristics, and Long-term Outcome of Dogs with Cranial Meningocele or Meningoencephalocele
Lazzerini, K. (University of Glasgow)
Gutierrez-Quintana, R. (University of Glasgow)
José-López, R. (University of Glasgow)
McConnell, F. (University of Liverpool)
Gonçalves, R. (University of Liverpool)
McMurrough, J. (PetMedics)
De Decker, S. (University of London. Royal Veterinary College (Hatfield, Regne Unit))
Muir, C. (University of London. Royal Veterinary College (Hatfield, Regne Unit))
Priestnall, S. L. (University of London. Royal Veterinary College (Hatfield, Regne Unit))
Mari, L. (Animal Health Trust)
Stabile, F. (Animal Health Trust)
De Risio, Luisa (Animal Health Trust)
Loeffler, C. (University of Leipzig)
Tauro, A. (Fitzpatrick Referrals)
Rusbridge, C. (Fitzpatrick Referrals)
Rodenas, S. (Hospital Veterinario Valencia Sur)
Añor Torres, Sònia (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
de la Fuente, Cristian (Universitat Autònoma de Barcelona. Hospital Clínic Veterinari)
Fischer, A. (Ludwig-Maximilian University Munich)
Bruehschwein, A. (Ludwig-Maximilian University Munich)
Penderis, J. (Broadleys Veterinary Hospital)
Guevar, J. (University of Glasgow)

Data: 2017
Resum: The term meningoencephalocele () describes a herniation of cerebral tissue and meninges through a defect in the cranium, whereas a meningocele () is a herniation of the meninges alone. To describe the clinical features, magnetic resonance imaging () characteristics, and outcomes of dogs with cranial and . Twenty-two client-owned dogs diagnosed with cranial or . Multicentric retrospective descriptive study. Clinical records of 13 institutions were reviewed. Signalment, clinical history, neurologic findings and characteristics as well as treatment and outcome were recorded and evaluated. Most affected dogs were presented at a young age (median, 6. 5 months; range, 1 month - 8 years). The most common presenting complaints were seizures and behavioral abnormalities. Intranasal was more common than parietal . Magnetic resonance imaging identified meningeal enhancement of the protruded tissue in 77% of the cases. Porencephaly was seen in all cases with parietal . Cerebrospinal fluid () analysis identified mild abnormalities in 4 of 11 cases. Surgery was not performed in any affected dog. Seventeen patients were treated medically, and seizures were adequately controlled with anti-epileptic drugs in 10 dogs. Dogs with intranasal and mild neurologic signs had a fair prognosis with medical treatment. Although uncommon, and should be considered as a differential diagnosis in young dogs presenting with seizures or alterations in behavior. Medical treatment is a valid option with a fair prognosis when the neurologic signs are mild.
Drets: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Llengua: Anglès
Document: Article ; recerca ; Versió publicada
Matèria: Cerebral malformation ; Cranioschisis ; Porencephaly ; Seizures
Publicat a: Journal of Veterinary Internal Medicine, Vol. 31 (february 2017) , p. 505-512, ISSN 1939-1676

DOI: 10.1111/jvim.14638
PMID: 28247440


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