| Imprint: |
[Barcelona] : Universitat Autònoma de Barcelona, 2017. |
| Description: |
1 recurs en línia (84 pàgines) |
| Abstract: |
The clinical criteria for defining intraabdominal candidiasis (IAC) are not specific, although a recent European consensus of experts shortened the definition of an IAC episode [10]. Inter-national guidelines focus mostly on candidemia and make little reference to antifungal therapy for IAC [11,12]. Patients in the intensive care unit (ICU) are at the highest risk for invasive candidiasis, mostly due to the severity of their disease immune-suppressive states, pro-longed length of stay, septic shock and Candidacolonization. Colonization occurs in the ICU population during the first week in up to 80% of cases [7,13], but few develop an ensuing se-vere infection [14]. The pathophysiology route of infection will determine the clinical scenario [15]; indeed, during a large recent study [9] focusing on intra-abdominal candidiasis, only 14% patients also developed candidemiaDelay in the initiation of treatment for invasive candidiasis has been associated with increased mortality [16-18]. It remains unclear which patients should receive empirical treatment or which not. According to current guidelines, appropriate treatment is based on azoles, poly-enes or echinocandins; however, the differences between these groups according to thetreatment of IAC have not been assessed, neither the differences between those more severe than those in regular wards. |
| Note: |
Tesi. Doctorat. Universitat Autònoma de Barcelona. Departament de Medicina. 2017. |
| Rights: |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.  |
| Language: |
Anglès |
| Document: |
Tesi doctoral ; Versió publicada |
| Subject: |
Candidiasi ;
Septicèmia |
| ISBN: |
9788449074011 |
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