Nasal Granuloma Caused by Scedosporium apiospermum in a Dog
Cabañes Sáenz, Francisco Javier (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Roura, Xavier (Universitat Autònoma de Barcelona. Hospital Clínic Veterinari)
Domingo, Mariano (Universitat Autònoma de Barcelona. Departament de Patologia i de Producció Animals)
Abarca Salat, Maria Lourdes (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
Pastor Milán, Josep (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
García Arnas, Félix (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)

Date:	1998
Abstract:	A 10-month-old male American Staffordshire terrier was presented to the Autonomous University of Barcelona Veterinary Teaching Hospital because of a 6-month history of a mucopurulent bilateral nasal discharge. The dog had not responded to antibiotics. A follow-up X ray revealed a mixed pattern of osteolysis and increased radiodensity confined to the nasal cavity. Histologic sections of the biopsy specimens revealed the presence of granules containing numerous septate hyphae that were hyaline to pale brown and smooth, one-celled, subspherical-to-elongate conidia that were hyaline to brownish green, and bacteria. Cultures yielded numerous colonies belonging to Scedosporium apiospermum. Susceptibility tests were performed on the isolated strain. The isolate was sensitive to ketoconazole, intermediate to clotrimazole, and resistant to amphotericin B, 5-fluorocytosine, fluconazole, and itraconazole. The dog was treated with oral ketoconazole. During the treatment a general improvement in the lesions was observed. To our knowledge, S. apiospermum has not been implicated previously as an etiologic agent of nasal disease in dogs. This report provides its first description as such.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Micologia Veterinària
Published in:	Journal of clinical microbiology, Vol. 36 Núm. 9 (Setembre 1998) , p. 2755-2758, ISSN 0095-1137

DOI: 10.1128/JCM.36.9.2755-2758.1998
PMID: 9705431

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Veterinary Mycology Group
Articles > Research articles
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