Web of Science: 17 citations, Scopus: 17 citations, Google Scholar: citations,
Direct and label-free detection of the human growth hormone in urine by an ultrasensitive bimodal waveguide biosensor
González-Guerrero, Ana Belén (Institut Català de Nanociència i Nanotecnologia)
Maldonado, Jesús (Institut Català de Nanociència i Nanotecnologia)
Dante, Stefania (Institut Català de Nanociència i Nanotecnologia)
Grajales García, Daniel (Institut Català de Nanociència i Nanotecnologia)
Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)

Date: 2017
Abstract: A label-free interferometric transducer showing a theoretical detection limit for homogeneous sensing of 5 × 10⁻⁸ RIU, being equivalent to a protein mass coverage resolution of 2. 8 fg mm⁻², is used to develop a high sensitive biosensor for protein detection. The extreme sensitivity of this transducer combined with a selective bioreceptor layer enables the direct evaluation of the human growth hormone (hGH) in undiluted urine matrix in the 10 pg mL⁻¹ range. (Figure presented. ).
Note: Número d'acord de subvenció MINECO/SEV-2013-0295
Note: Número d'acord de subvenció MICINN/TEC2012-34280
Note: Número d'acord de subvenció AGAUR/2014/SGR-624
Rights: Tots els drets reservats.
Language: Anglès.
Document: article ; recerca ; acceptedVersion
Subject: BiMW interferometer ; Silicon nanowaveguides ; Label-free biosensing ; Hgh detection ; Pg/ml detection range
Published in: Journal of biophotonics, Vol. 10, issue 1 (Jan. 2017) , p. 61-67, ISSN 1864-0648

DOI: 10.1002/jbio.201600154


Postprint
16 p, 406.9 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (scientific output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles

 Record created 2018-09-18, last modified 2020-02-29



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