Gold/silver/gold trilayer films on nanostructured polycarbonate substrates for direct and label-free nanoplasmonic biosensing
López Muñoz, Gerardo Arturo (Institut Català de Nanociència i Nanotecnologia)
Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia)
Vázquez García, Marc (Institut Català de Nanociència i Nanotecnologia)
Berenguel-Alonso, Miguel (Universitat Autònoma de Barcelona. Departament de Química)
Alonso Chamarro, Julián (Universitat Autònoma de Barcelona. Departament de Química)
Homs Corbera, Antoni (Institut Català de Nanociència i Nanotecnologia)
Lechuga, Laura M (Institut Català de Nanociència i Nanotecnologia)

Date:	2018
Abstract:	Ultrasmooth gold/silver/gold trilayer nanostructured plasmonic sensors were obtained using commercial Blu-ray optical discs as nanoslits-based flexible polymer substrates. A thin gold film was used as an adhesion and nucleation layer to improve the chemical stability and reduce the surface roughness of the overlying silver film, without increasing ohmic plasmon losses. The structures were physically and optically characterized and compared with nanostructures of single gold layer. Ultrasmooth and chemically stable trilayer nanostructures with a surface roughness <0. 5 nm were obtained following a simple and reproducible fabrication process. They showed a figure of merit (FOM) value up to 69. 2 RIU which is significantly higher (more than 95%) than the gold monolayer counterpart. Their potential for biosensing was demonstrated by employing the trilayer sensor for the direct and refractometric (label-free) detection of C-reactive protein (CRP) biomarker in undiluted urine achieving a Limit of Detection (LOD) in the pM order.
Grants:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2014/SGR-624 Ministerio de Economía y Competitividad SEV-2013-0295 Ministerio de Economía y Competitividad TEC2016-78515-R
Note:	Altres ajuts: CONACYT, Grant/Award Number: 225362
Rights:	Tots els drets reservats.
Language:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Subject:	Blu-ray disc ; Flexible substrate ; Nanoplasmonic devices ; Nucleation layer ; Silver nanoslits
Published in:	Journal of biophotonics, Vol. 11, Issue 8 (August 2018) , art. e201800043, ISSN 1864-0648

DOI: 10.1002/jbio.201800043

Postprint 17 p, 1.3 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles