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Pàgina inicial > Articles > Articles publicats > Design strategies for shape-controlled magnetic iron oxide nanoparticles |
Data: | 2019 |
Resum: | Ferrimagnetic iron oxide nanoparticles (magnetite or maghemite) have been the subject of an intense research, not only for fundamental research but also for their potentiality in a widespread number of practical applications. Most of these studies were focused on nanoparticles with spherical morphology but recently there is an emerging interest on anisometric nanoparticles. This review is focused on the synthesis routes for the production of uniform anisometric magnetite/maghemite nanoparticles with different morphologies like cubes, rods, disks, flowers and many others, such as hollow spheres, worms, stars or tetrapods. We critically analyzed those procedures, detected the key parameters governing the production of these nanoparticles with particular emphasis in the role of the ligands in the final nanoparticle morphology. The main structural and magnetic features as well as the nanotoxicity as a function of the nanoparticle morphology are also described. Finally, the impact of each morphology on the different biomedical applications (hyperthermia, magnetic resonance imaging and drug delivery) are analysed in detail. We would like to dedicate this work to Professor Carlos J. Serna, Instituto de Ciencia de Materiales de Madrid, ICMM/CSIC, for his outstanding contribution in the field of monodispersed colloids and iron oxide nanoparticles. We would like to express our gratitude for all these years of support and inspiration on the occasion of his retirement. |
Ajuts: | European Commission 604448 Ministerio de Economía y Competitividad MAT2016-77391-R Ministerio de Economía y Competitividad MAT2017-88148-R Ministerio de Economía y Competitividad RYC-2014-15512 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-292 Ministerio de Economía y Competitividad SEV-2017-0706 |
Drets: | Tots els drets reservats. |
Llengua: | Anglès |
Document: | Article ; recerca ; Versió sotmesa a revisió |
Matèria: | Magnetic nanoparticles ; Anisometric nanoparticles ; Shape anisotropy ; Nanocubes ; Rods ; Disks ; Nanoflowers ; Hollow nanoparticles ; Nanotoxicity ; Biomedical applications |
Publicat a: | Advanced drug delivery reviews, Vol. 138 (January 2019) , p. 68-104, ISSN 1872-8294 |
Preprint 89 p, 3.5 MB |