The fresh water mussel unio mancus as sentinel for antibiotic-resistant enterobacteriaceae present in inland waters
Lobato Bailón, Lourdes

Data: 2019
Descripció: 38 p.
Resum: Freshwater mussels are known to provide ecosystem services in many ways. Their natural filter-feeding activity contributes to maintenance of water sources and also, they are considered good bio-indicators of water contamination. Unio mancus is a threatened naiad inhabiting inland freshwaters from the Mediterranean basin, whose population has been decreasing mainly due to degradation of the habitat by human activities. In the present study, U. mancus was tested as a tool for detecting Enterobacteriaceae from inland freshwater. For that purpose, two experiments were carried out. The first one evaluated the capability of these naiads to filter and retain inoculated cephalosporin-resistant E. coli in laboratory conditions. They proved to maintain bacterial loads in their soft tissue up to 4 days post-exposure. The second experiment was carried out between July 2018 and April 2019 along L'Estany de Banyoles Lake and its scraping irrigations. To determine the presence of antimicrobial-resistant Enterobacteriaceae under different levels of anthropogenic pressure, underwater caged naiads were tested for five periods of 15 consecutive days. Among all isolated bacteria using Vitek®2 system, six MDR-E. coli and one MDR-Klebsiella pneumoniae were found in the most anthroponized and polluted location points. Minimum inhibitory concentrations (MIC) for these bacteria were interpreted according to the Epidemiological cut-off (ECOFF) values from the European Committee in Antimicrobial Susceptibility Testing (EUCAST). Our results suggest that U. mancus has potential to become sentinel of bacterial pathogens of Public Health concern. A better understanding of their filtration capability will provide insights into more accurate cost-benefit analyses for their repopulation in autochthonous freshwater systems.
Drets: L'accés als continguts d'aquest document queda condicionat a l'acceptació de les condicions d'ús establertes per la següent llicència Creative Commons: Creative Commons
Llengua: Anglès
Col·lecció: Facultat de Veterinària. Treballs de màster i postgrau. Màster Oficial - Zoonosi i Una Sola Salut (ONE HEALTH)
Document: masterThesis
Matèria: Musclos ; Microorganismes ; Resistència als medicaments

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38 p, 1.8 MB

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