Validation of cancer diagnoses in electronic health records : Results from the information system for research in primary care (SIDIAP) in northeast spain
Recalde, Martina (Universitat Autònoma de Barcelona)
Manzano-Salgado, Cyntia B. (Universitat Autònoma de Barcelona)
Díaz, Yesika (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Puente, Diana (Universitat Autònoma de Barcelona)
Garcia-Gil, Maria del Mar (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Marcos-Gragera, Rafael (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Ribes-Puig, Josefa (Universitat de Barcelona. Departament de Ciències Clíniques)
Galceran, Jaume (Registre de Càncer de Tarragona. Fundació per a la Investigació i Prevenció del Càncer (FUNCA). IISPV)
Posso, Margarita (Hospital del Mar (Barcelona, Catalunya))
Macià, Francesc (Hospital del Mar (Barcelona, Catalunya))
Duarte-Salles, Talita 1985- (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)

Data:	2019
Resum:	Background: Electronic health records are becoming an increasingly valuable resource for epidemiology but their data quality needs to be quantified. We aimed to validate twenty-five types of incident cancer cases in the Information System for Research in Primary Care (SIDIAP) in Catalonia with the population-based cancer registries of Girona and Tarragona as the gold-standard. Methods: We calculated the sensitivity, positive predictive values (PPV), and the timedifference between the date of diagnosis entered into the SIDIAP and into the registries. We added hospital discharge cancer diagnoses to the SIDIAP to assess sensitivity changes. Results: We identified 27,046 incident cancer diagnoses in the SIDIAP from 2009-2015 among the 949,841 residents of Girona and Tarragona. The cancer types with the highest sensitivity were breast (89%, 95% CI: 88-90%), colorectal (81%, 95% CI: 80-82%), and prostate (81%, 95% CI: 80-83%). Trachea, bronchus and lung cancers had the highest PPV (76%, 95% CI: 74%-78%) followed by stomach (72%, 95% CI: 68-75%) and pancreas (71%, 95% CI: 67-75%). Most cancer diagnoses were reported with less than three months of difference between the SIDIAP and the registries. More cases were registered first in the registries than in the SIDIAP. By adding cancer diagnoses based on hospital discharge data, sensitivity increased for all cancers, especially for gallbladder and biliary tract for which the sensitivity increased by 21%. Conclusion: The SIDIAP includes 76% of the cancer diagnoses in the cancer registries but includes a considerable number of cases that are not in the registries. The SIDIAP reports most of the cancer diagnoses within a three-month period difference from the date of diagnosis in the cancer registries. Our results support the use of the SIDIAP cancer diagnoses for epidemiological research when cancer is the outcome of interest. We recommend adding hospital discharge data to the SIDIAP to increase data quality, particularly for less frequent cancer types.
Ajuts:	Agència de Gestió d'Ajuts Universitaris i de Recerca SLT002/16/00308
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Validation studies ; Cancer ; Electronic health records ; Primary health care ; Population-based cancer registries
Publicat a:	Clinical Epidemiology, Vol. 11 (2019) , p. 1015-1024, ISSN 1179-1349

DOI: 10.2147/CLEP.S225568
PMID: 31819655

10 p, 2.0 MB

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