Prognostic value of discharge heart rate in acute heart failure patients : More relevant in atrial fibrillation?
Rosa, Agra Bermejo (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
Domingo, Pascual-Figal (Hospital Universitario Virgen de la Arrixaca (Múrcia))
Francisco, Gude Sampedro (Hospital Clínico Universitario (Santiago de Compostela, Galícia))
Juan, Delgado Jiménez (Hospital Universitario 12 de Octubre (Madrid))
Rafael, Vidal Pérez (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
Inés, Gómez Otero (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
Andreu, Ferrero-Gregori (Institut d'Investigació Biomèdica Sant Pau)
Jesús, Álvarez-García (Institut d'Investigació Biomèdica Sant Pau)
Fernando, Worner Diz (Hospital Arnau de Vilanova (Lleida, Catalunya))
Jesús, Segovia (Hospital Universitario Puerta de Hierro Majadahonda (Madrid))
María Generosa, Crespo-Leiro (Complejo Hospitalario Universitario de A Coruña)
Cinca, Juan (Institut d'Investigació Biomèdica Sant Pau)
Francisco, Fernández Avilés (Hospital General Universitario Gregorio Marañón)
Jose Ramón, Gónzalez-Juanatey (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares)
Universitat Autònoma de Barcelona

Date:	2019
Abstract:	The prognostic impact of heart rate (HR) in acute heart failure (AHF) patients is not well known especially in atrial fibrillation (AF) patients. The aim of the study was to evaluate the impact of admission HR, discharge HR, HR difference (admission-discharge) in AHF patients with sinus rhythm (SR) or AF on long- term outcomes. We included 1398 patients consecutively admitted with AHF between October 2013 and December 2014 from a national multicentre, prospective registry. Logistic regression models were used to estimate the association between admission HR, discharge HR and HR difference and one- year all-cause mortality and HF readmission. The mean age of the study population was 72 ± 12 years. Of these, 594 (42. 4%) were female, 655 (77. 8%) were hypertensive and 655 (46. 8%) had diabetes. Among all included patients, 745 (53. 2%) had sinus rhythm and 653 (46. 7%) had atrial fibrillation. Only discharge HR was associated with one year all-cause mortality (Relative risk (RR) = 1. 182, confidence interval (CI) 95% 1. 024-1. 366, p = 0. 022) in SR. In AF patients discharge HR was associated with one year all cause mortality (RR = 1. 276, CI 95% 1. 115-1. 459, p ≤ 0. 001). We did not observe a prognostic effect of admission HR or HRD on long-term outcomes in both groups. This relationship is not dependent on left ventricular ejection fraction. In AHF patients lower discharge HR, neither the admission nor the difference, is associated with better long-term outcomes especially in AF patients.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Heart rate ; Acute heart failure ; Sinus rhythm ; Atrial fibrillation ; Mortality
Published in:	International journal of cardiology. Heart & vasculature, Vol. 26 (december 2019) , ISSN 2352-9067

DOI: 10.1016/j.ijcha.2019.100444
PMID: 32140546

6 p, 698.8 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles