Nivolumab-Induced Bullous Pemphigoid Managed without Drug Withdrawal
Munera-Campos, Monica (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Plana Pla, Adrià (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Rivera, Noelia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Boada, Aram (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Ferrándiz, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Universitat Autònoma de Barcelona

Date:	2020
Abstract:	The widespread use of anti-programmed cell death receptor-1 (PD-1) agents has shed light to unusual immune-related adverse effects, especially affecting the skin. We report a case of bullous pemphigoid secondary to nivolumab therapy for metastatic renal carcinoma with a previously unreported complete response to clobetasol ointment alone. The autoimmune blistering disease was successfully treated without oral corticosteroids, and the anti-PD-1 agent could be maintained without recurrence of the skin lesions. Topical therapy remains a good option in selected, mild-to-moderate cases of induced bullous pemphigoid.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Anti-programmed cell death receptor-1 ; Bullous pemphigoid ; Nivolumab ; Renal carcinoma ; Topical treatment
Published in:	Indian Journal of Dermatology, Vol. 65 (2020) , p. 214-216, ISSN 1998-3611

DOI: 10.4103/ijd.IJD_321_18
PMID: 32565564

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles