Conflicts of interest in research on electronic cigarettes
Martínez, Cristina (Universitat de Barcelona. Facultat de Medicina i Ciències de la Salut)
Fu, Marcela (Universitat de Barcelona. Departament de Ciències Clíniques)
Galán, Ignacio (Universidad Autónoma de Madrid. Departamento de Medicina Preventiva y Salud Pública)
Pérez-Ríos, Mónica (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Martínez-Sánchez, Jose M. (Universitat Internacional de Catalunya. Facultat de Medicina)
López, Maria J. (Institut d'Investigació Biomèdica Sant Pau)
Sureda, Xisca (Social and Cardiovascular Epidemiology Research Group, School of Medicine, Universidad de Alcalá, Madrid, Spain)
Montes, Agustín (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública)
Fernández, Esteve (Universitat de Barcelona. Departament de Ciències Clíniques)
Universitat Autònoma de Barcelona

Fecha:	2018
Resumen:	The tobacco control community has raised some concerns about whether studies on electronic cigarettes (e-cigarettes) published in scientific journals hide conflicts of interest (COI) and whether such reports are biased. This study assessed potential COI in the e-cigarette scientific literature. Cross-sectional study was conducted on e-cigarette publications indexed in PubMed up to August 2014. We extracted information about the authors (affiliations, location, etc. ), publication characteristics (type, topic, subject, etc. ), results and conclusions, presence of a COI statement, and funding by and/or financial ties to pharmaceutical, tobacco, and/or e-cigarette companies. An algorithm to determine the COI disclosure status was created based on the information in the publication. Prevalence ratios (PRs) and confidence intervals (CIs) were calculated to identify associations with COI disclosure, controlling for several independent variables. Of the 404 publications included in the analysis, 37. 1% (n=150) had no COI disclosure statement, 38. 6% declared no COI, 13. 4% declared potential COI with pharmaceutical companies, 3. 0% with tobacco companies, and 10. 6% with e-cigarette companies. The conclusions in publications with COI, which were mainly tied to pharmaceutical companies, were more likely to be favourable to e-cigarette use (PR=2. 23; 95% CI: 1. 43-3. 46). Publications that supported the use of e-cigarettes for both harm reduction (PR=1. 81; 95%CI: 1. 14-2. 89) and smoking cessation (PR=2. 02; 95% CI: 1. 26-3. 23) were more likely to have conclusions that were favourable to e-cigarettes. One-third of the publications reporting studies on e-cigarettes did not have a COI disclosure statement, and this proportion was even higher in news articles, editorials and other types of publications. Papers with conclusions that were favourable to e-cigarette use were more likely to have COI. Journal editors and reviewers should consider evaluating publications, including funding sources, to determine whether the results and conclusions may be biased.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Conflicts of interest ; Electronic cigarettes ; Bibliography as topic
Publicado en:	Tobacco Induced Diseases, Vol. 16 (june 2018) , ISSN 1617-9625

DOI: 10.18332/tid/90668
PMID: 31516428

12 p, 574.2 KB

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