Web of Science: 19 citations, Scopus: 20 citations, Google Scholar: citations
Long-Term Dynamics of Bluetongue Virus in Wild Ruminants : relationship with Outbreaks in Livestock in Spain, 2006-2011
Lorca Oró, Cristina (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal (CReSA-IRTA))
López Olvera, Jorge R. (Universitat Autònoma de Barcelona. Servei d'Ecopatologia de Fauna Salvatge)
Ruiz-Fons, Francisco (Instituto de Investigación en Recursos Cinegéticos)
Acevedo, Pelayo (Instituto de Investigación en Recursos Cinegéticos)
García-Bocanegra, Ignacio (Universidad de Córdoba. Departamento de Sanidad Animal)
Oleaga, Álvaro (Instituto de Investigación en Recursos Cinegéticos)
Gortázar, Christian
Pujols, Joan (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal (CReSA-IRTA))

Date: 2014
Abstract: Wild and domestic ruminants are susceptible to Bluetongue virus (BTV) infection. Three BTV serotypes (BTV-4, BTV-1 and BTV-8) have been detected in Spain in the last decade. Even though control strategies have been applied to livestock, BTV circulation has been frequently detected in wild ruminant populations in Spain. The aim of the present study is to assess the role for wild ruminants in maintaining BTV after the vaccination programs in livestock in mainland Spain. A total of 931 out 1,914 (48. 6%) serum samples, collected from eight different wild ruminant species between 2006 and 2011, were BTV positive by ELISA. In order to detect specific antibodies against BTV-1, BTV-4 and BTV-8, positive sera were also tested by serumneutralisation test (SNT). From the ELISA positive samples that could be tested by SNT (687 out of 931), 292 (42. 5%) showed neutralising antibodies against one or two BTV serotypes. For each BTV seroptype, the number of outbreaks in livestock (11,857 outbreaks in total) was modelled with pure autoregressive models and the resulting smoothed values, representing the predicted number of BTV outbreaks in livestock at municipality level, were positively correlated with BTV persistence in wild species. The strength of this relationship significantly decreased as red deer (Cervus elaphus) population abundance increased. In addition, BTV RNA was detected by real time RT-PCR in 32 out of 311 (10. 3%) spleen samples from seropositive animals. Although BT outbreaks in livestock have decreased substantially after vaccination campaigns, our results indicated that wild ruminants have been exposed to BTV in territories where outbreaks in domestic animals occurred. The detection of BTV RNA and spatial association between BT outbreaks in livestock and BTV rates in red deer are consistent with the hypothesis of virus circulation and BTV maintenance within Iberian wild ruminant populations.
Note: Número d'acord de subvenció INIA/FAU2008-00019-C03-01 PMEC/SFRH/BPD/90320/2012
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: article ; recerca ; publishedVersion
Subject: Llengua blava ; Remugants -- Malalties ; Animals salvatges -- Malalties
Published in: PloS one, Vol. 9 Núm. 6 (Juny 2014) , ISSN 1932-6203

DOI: 10.1371/journal.pone.0100027
PMID: 24940879


8 p, 651.4 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (scientific output) > Health sciences and biosciences > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Research literature > UAB research groups literature > Research Centres and Groups (scientific output) > Health sciences and biosciences > Research group Wildlife Ecology & Health
Articles > Research articles
Articles > Published articles

 Record created 2020-11-18, last modified 2020-11-24



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