Motor Cortex Plasticity during Unilateral Finger Movement with Mirror Visual Feedback
Kumru, Hatice (Institut Germans Trias i Pujol. Institut Guttmann)
Albu, Sergiu (Texas A&M University, College Station, TX 77843-4235, USA)
Pelayo, Raul (Institut Germans Trias i Pujol. Institut Guttmann)
Rothwell, John (Institute of Neurology, University College London, London WC1N 3BG, UK)
Opisso, Eloy (Institut Germans Trias i Pujol. Institut Guttmann)
Leon, Daniel (Institut Germans Trias i Pujol. Institut Guttmann)
Soler, Dolor (Institut Germans Trias i Pujol. Institut Guttmann)
Tormos, Josep Maria (Institut Germans Trias i Pujol. Institut Guttmann)
Universitat Autònoma de Barcelona

Date:	2015
Abstract:	Plasticity is one of the most important physiological mechanisms underlying motor recovery from brain lesions. Rehabilitation methods, such as mirror visual feedback therapy, which are based on multisensory integration of motor, cognitive, and perceptual processes, are considered effective methods to induce cortical reorganization. The present study investigated 3 different types of visual feedback (direct, mirrored, and blocked visual feedback: DVF, MVF, and BVF, resp. ) on M1 cortex excitability and intracortical inhibition/facilitation at rest and during phasic unimanual motor task in 11 healthy individuals. The excitability of the ipsilateral M1 cortex and the intracortical facilitation increased during motor task performance in the DVF and MVF but not in the BVF condition. In addition, MVF induced cortical disinhibition of the ipsilateral hemisphere to the index finger performing the motor task, which was greater when compared to the BVF and restricted to the homologue first dorsal interosseous muscle. The visual feedback is relevant to M1 cortex excitability modulation but the MVF plays a crucial role in promoting changes in intracortical inhibition in comparison to BVF. Altogether, it can be concluded that a combination of motor training with MVF therapy may induce more robust neuroplastic changes through multisensory integration that is relevant to motor rehabilitation.
Note:	Altres ajuts: This work was supported in part by grants from Foundation La Marato TV3 PI110932 to Hatice Kumru.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	Neural plasticity, Vol. 2016 (december 2015) , ISSN 1687-5443

DOI: 10.1155/2016/6087896
PMID: 26881121

8 p, 1.4 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles