The EANM practice guidelines for parathyroid imaging
Petranović Ovčariček, Petra (University Hospital Center "Sestre milosrdnice". Department of Oncology and Nuclear medicine)
Giovanella, Luca (University Hospital and University of Zurich. Clinic for Nuclear Medicine and Interdisciplinary Thyroid Centre)
Carrió, Ignasi (Institut d'Investigació Biomèdica Sant Pau)
Hindié, Elif (Bordeaux University Hospital (França))
Huellner, Martin W. (University Hospital Zurich (Suïssa))
Luster, Markus (University Hospital of Giessen and Marburg (Alemanya))
Piccardo, Arnoldo (E.O. Ospedali Galliera. Department of Nuclear Medicine)
Weber, Theresia (Department of Endocrine Surgery, Katholisches Klinikum Mainz, Mainz, Germany)
Talbot, Jean-Noël (Hospital Tenon APHP and Sorbonne University. Nuclear Medicine)
Verburg, Frederik Anton (Erasmus MC. Department of Radiology and Nuclear Medicine)
Universitat Autònoma de Barcelona

Date:	2021
Abstract:	Nuclear medicine parathyroid imaging is important in the identification of hyperfunctioning parathyroid glands in primary hyperparathyroidism (pHPT), but it may be also valuable before surgical treatment in secondary hyperparathyroidism (sHPT). Parathyroid radionuclide imaging with scintigraphy or positron emission tomography (PET) is a highly sensitive procedure for the assessment of the presence and number of hyperfunctioning parathyroid glands, located either at typical sites or ectopically. The treatment of pHPT is mostly directed toward minimally invasive parathyroidectomy, especially in cases with a single adenoma. In experienced hands, successful surgery depends mainly on the exact preoperative localization of one or more hyperfunctioning parathyroid adenomas. Failure to preoperatively identify the hyperfunctioning parathyroid gland challenges minimally invasive parathyroidectomy and might require bilateral open neck exploration. Over a decade has now passed since the European Association of Nuclear Medicine (EANM) issued the first edition of the guideline on parathyroid imaging, and a number of new insights and techniques have been developed since. The aim of the present document is to provide state-of-the-art guidelines for nuclear medicine physicians performing parathyroid scintigraphy, single-photon emission computed tomography/computed tomography (SPECT/CT), positron emission tomography/computed tomography (PET/CT), and positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with pHPT, as well as in those with sHPT. These guidelines are written and authorized by the EANM to promote optimal parathyroid imaging. They will assist nuclear medicine physicians in the detection and correct localization of hyperfunctioning parathyroid lesions.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; altres ; Versió publicada
Subject:	Parathyroid scintigraphy ; Hyperparathyroidism ; [ 99m Tc]Tc-MIBI ; [ 99m Tc]Tc-tetrofosmin ; SPECT/CT ; Dual-phase scintigraphy ; Dual-tracer scintigraphy ; 18 F-labeled choline analogues ; [ 11 C]CH ; [ 11 C]MET ; PET/CT ; Cervical ultrasonography ; 4D-CT ; MRI
Published in:	European Journal of Nuclear Medicine and Molecular Imaging, Vol. 48 (april 2021) , p. 2801-2822, ISSN 1619-7089

DOI: 10.1007/s00259-021-05334-y
PMID: 33839893

22 p, 640.9 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Published articles