Vaccines against antimicrobial resistance (AMR) in enterobacteriaceae
Planells i Romeo, Violeta
Yero, Daniel, dir. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Universitat Autònoma de Barcelona. Facultat de Biociències

Fecha:	2021
Resumen:	Enterobacteriaceae is a group of nosocomial pathogens that can colonize various sites and cause serious infections when host defenses are compromised. In this group of bacteria multi-drug resistant organisms have been described. AMR keeps spreading and while antibiotic development will always be subjected to the appearance of resistance, vaccines elicit protective immunity that could prevent transmission and infection and therefore, reduce or revert antimicrobial resistance. Yet, vaccines against critical enterobacteria need to be reassessed. Advances in vaccinology techniques, together with the identification of new targets, may allow a change in the vaccine design strategy, towards a more strain-specific approach. However, there are still many challenges directly related to the opportunistic nature of this pathogens and therefore, other alternative treatments with a therapeutic approach (e. g. mAb vaccines) should be also considered for this field.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Anglès
Titulación:	Biologia [2500250]
Plan de estudios:	Grau en Biologia [812]
Documento:	Treball final de grau ; Text
Materia:	Enterobacteriaceae ; Antimicrobial resistance ; Vaccines

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Documentos de investigación > Trabajos de Fin de Grado > Facultat de Biociencias. TFG