Recreational Drug Use in People Living with HIV in Spain : Factors Associated with Drug Use and the Impact on Clinical Outcomes
Castro, Vanessa (Hospital Marina Baixa (La Vila Joiosa, Alacant))
Garin, Noe (Institut d'Investigació Biomèdica Sant Pau)
Jaén, Ángeles (Universitat de Barcelona)
Casado, José Luis (Hospital Universitario Ramón y Cajal (Madrid))
Leal, Lorna (Hospital Clínic i Provincial de Barcelona)
Cenoz, Santiago (ViiV Healthcare)
Fuster-RuizdeApodaca, María José (Universidad Nacional de Educación a Distancia (Espanya))

Date:	2021
Abstract:	We analysed the impact of recreational drug use (RDU) on different outcomes in people living with HIV (PLHIV). A multicentre retrospective cohort study was performed with two cohorts of PLHIV included: people using recreational drugs (PURD) vs. people not using recreational drugs (PNURD). Overall, 275 PLHIV were included. RDU was associated with men having sex with men (OR 4. 14, 95% CI [1. 14, 5. 19]), previous sexually transmitted infections (OR 4. 00, 95% CI [1. 97, 8. 13]), and current smoking (OR 2. 74, 95% CI [1. 44, 5. 19]). While the CD/CD ratio increased amongst PNURD during the follow-up year, it decreased amongst PURD (p = 0. 050). PURD presented lower scores of self-reported and multi-interval antiretroviral adherence (p = 0. 017, and p = 0. 006, respectively), emotional well-being (p < 0. 0001), and regular follow-up (p = 0. 059), but paid more visits to the emergency unit (p = 0. 046). RDU worsens clinical, immunological, and mental health outcomes amongst PLHIV.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	HIV ; Recreational drug use ; Antiretroviral therapy ; Clinical outcomes ; VIH ; Drogas recreativas ; Terapia antiretroviral ; Resultados clínicos
Published in:	AIDS and Behavior, Vol. 25 (may 2021) , p. 3883-3897, ISSN 1573-3254

DOI: 10.1007/s10461-021-03271-3
PMID: 33932187

15 p, 910.6 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles