Evolution of Patient Perceptions of Psoriatic Disease : Results from the Understanding Psoriatic Disease Leveraging Insights for Treatment (UPLIFT) Survey
Lebwohl, Mark (Icahn School of Medicine at Mount Sinai)
Langley, Richard G. (Dalhousie University)
Paul, Carle (Paul Sabatier University)
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau)
Reich, Kristian (University Medical Center Hamburg-Eppendorf)
van de Kerkhof, Peter (Radboud University Medical Center)
Wu, Hsiuan-Lin (Amgen Inc)
Richter, Sven (Amgen Inc)
Jardon, Shauna (Amgen Inc)
Gisondi, Paolo (University Hospital of Verona (Itàlia))
Universitat Autònoma de Barcelona

Fecha:	2021
Resumen:	Since the 2012 Multinational Assessment of Psoriasis and Psoriatic Arthritis (MAPP) survey, several systemic treatments for psoriasis (PsO) and/or psoriatic arthritis (PsA) have been approved. The population-based UPLIFT survey was conducted to understand how perceptions of treatment-related outcomes have evolved, particularly for patients with mild to moderate PsO and/or PsA and their dermatologists. This population- and web-based survey was conducted from 2 March to 3 June 2020, in North America, Europe, and Japan. Adults with self-reported healthcare practitioner (HCP)-diagnosed PsO and/or PsA and dermatologists who spent > 50% of time treating patients and treated ≥ 20 patients with PsO, including plaque PsO, per month were included. Patient participants were recruited at random from online panels; dermatologists were recruited randomly from representative physician panels. Of 264,054 patient responses, 3806 who self-reported an HCP diagnosis of PsO and/or PsA were included in the final sample; 67% had PsO alone, 28% had PsO and PsA, and 5% had PsA alone. The estimated population prevalence of psoriatic disease was 7% (PsO only: 4%; PsO and PsA: 2%; PsA only: 1%). Most patients (78%) reported PsO-involved body surface area (BSA) ≤ 3 palms, and ~ 90% or more reported itching, redness, flaking, and scales. Many PsO patients without diagnosed PsA reported musculoskeletal symptoms suggestive of PsA (63%). Across BSA categories, approximately one in four patients was not currently receiving treatment and > 50% had Dermatology Life Quality Index score > 5. Patients and dermatologists had different perceptions of PsO severity, office visit discussions, treatment goals, and treatment satisfaction. The survey was conducted during the coronavirus disease 2019 (COVID-19) pandemic, which could have affected assessments of patient-reported outcomes and ability to have in-person HCP visits. Patients with PsO and PsA in UPLIFT reported high disease burden, including patients with limited skin involvement. An opportunity exists to align patient and dermatologist perceptions to optimize management of PsO and PsA. The online version contains supplementary material available at 10. 1007/s13555-021-00635-4. The online version contains supplementary material available at 10. 1007/s13555-021-00635-4.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Health survey ; Patient satisfaction ; Psoriasis ; Psoriatic arthritis ; Quality of life ; Special area ; Symptom ; Treatment
Publicado en:	Dermatology and Therapy, october 2021, p. 1-16, ISSN 2190-9172

Erratum: https://ddd.uab.cat/record/252160
DOI: 10.1007/s13555-021-00635-4
PMID: 34704231

16 p, 894.7 KB

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