Pharmacological treatment after acute coronary syndrome : Baseline clinical characteristics and gender differences in a population-based cohort study
Sotorra Figuerola, Gerard (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Ouchi, Dan (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Garcia-Sangenis, Ana (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Giner-Soriano, Maria (Institut Universitari d'Investigació en Atenció Primària Jordi Gol)
Morros, Rosa (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)

Data:	2021
Resum:	To describe baseline socio-demographic and clinical characteristics and drugs prescribed for secondary prevention after a first episode of ACS and to assess differences between men and women. PHC in Catalonia. Data source: SIDIAP (Information System for Research in Primary Care). Patients who suffered an ACS during 2009-2016 and followed-up in PHC centres of the Catalan Health Institute in Catalonia. Not applicable. Socio-demographic and clinical characteristics at baseline: sex, age, socioeconomic index, toxic habits, comorbidities, study drugs (prescribed for cardiovascular secondary prevention: antiplatelets, betablockers, statins, drugs acting on the renin-angiotensin system) and comedications. 8071 patients included, 71. 3% of them were men and 80. 2% had an acute myocardial infarction. Their mean age was 65. 3 and women were older than men. The most frequent comorbidities were hypertension, dyslipidaemia and diabetes and they were more common in women. Antiplatelets (91. 3%) and statins (85. 7%) were the study drugs most prescribed. The uses of all comedications were significantly higher in women, except for nitrates. The combination of four study groups was initially prescribed in 47. 7% of patients and combination of beta-blockers, statins and antiplatelets was prescribed in 18. 4%. More men than women received all recommended pharmacological groups. Women were older, had more comorbidities and received more comedications. Most patients were treated with a combination of four or three study drugs for secondary prevention. Men initiated more drug treatments for secondary prevention and dual antiplatelet therapy than women. EUPAS19017.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Electronic health records ; Acute coronary syndrome ; Drug adherence ; Secondary prevention ; Registros electrónicos de salud ; Síndrome coronario agudo ; Adherencia a la medicación ; Prevención secundaria
Publicat a:	Atencion Primaria, Vol. 54 (october 2021) , ISSN 1578-1275

DOI: 10.1016/j.aprim.2021.102157
PMID: 34717156

11 p, 1.3 MB

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