Cortical thickness across the lifespan : Data from 17,075 healthy individuals aged 3-90 years
Frangou, Sophia (University of British Columbia)
Modabbernia, Amirhossein (Icahn School of Medicine at Mount Sinai)
Williams, Steven C. R. (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
Papachristou, Efstathios (Institute of Education, University College London)
Doucet, Gaelle E. (Boys Town National Research Hospital)
Agartz, Ingrid (Karolinska Institutet (Estocolm, Suècia))
Aghajani, Moji (Institute of Education & Child Studies)
Akudjedu, Theophilus N. (National University of Ireland)
Albajes-Eizagirre, Anton (Centro de Investigación Biomédica en Red de Salud Mental)
Alnæs, Dag (Institute of Clinical Medicine, University of Oslo)
Alpert, Kathryn I. (Radiologics, Inc)
Andersson, Micael (Umeå University)
Andreasen, Nancy C. (The University of Iowa)
Andreassen, Ole A. (University of Oslo)
Asherson, Philip (King's College London)
Banaschewski, Tobias (Heidelberg University)
Bargalló, Núria (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Baumeister, Sarah (Heidelberg University)
Baur-Streubel, Ramona (University of Würzburg)
Bertolino, Alessandro (University of Bari Aldo Moro)
Bonvino, Aurora (Vrije Universiteit)
Boomsma, Dorret I. (Vrije Universiteit)
Borgwardt, Stefan (University of Lübeck)
Bourque, Josiane (University of Pennsylvania)
Brandeis, Daniel (Heidelberg University)
Breier, Alan (Indiana University School of Medicine)
Brodaty, Henry (University of New South Wales)
Brouwer, Rachel M. (University Medical Center Utrecht)
Buitelaar, Jan (Radboud University)
Busatto, Geraldo F. (Universidade de São Paulo)
Buckner, Randy (Massachusetts General Hospital (Boston))
Calhoun, Vince (Emory University)
Canales-Rodriguez, Erick Jorge (Centro de Investigación Biomédica en Red de Salud Mental)
Cannon, Dara M. (National University of Ireland)
Caseras, Xavier (Cardiff University)
Castellanos, Francisco X. (New York University)
Cervenka, Simon (Stockholm Health Care Services)
Chaim-Avancini, Tiffany M. (Universidade de São Paulo)
Ching, Christopher R. K. (University of Southern California)
Chubar, Victoria (KU Leuven)
Clark, Vincent P. (Mind Research Network)
Conrod, Patricia (Université de Montréal)
Conzelmann, Annette (University of Tübingen)
Crespo-Facorro, Benedicto (University of Sevilla)
Crivello, Fabrice (Université de Bordeaux)
Crone, Eveline A. (Universiteit Leiden)
Dale, Anders M. (University of California-San Diego)
Dannlowski, Udo (University of Münster)
Davey, Christopher (University of Melbourne)
de Geus, Eco J. C. (Vrije Universiteit)
de Haan, Lieuwe (Universiteit van Amsterdam)
de Zubicaray, Greig (Queensland University of Technology)
den Braber, A (Vrije Universiteit)
Dickie, Erin W. (University of Toronto)
Di Giorgio, Annabella (Fondazione IRCCS Casa Sollievo della Sofferenza)
Doan, Nhat Trung (University of Oslo)
Dørum, Erlend S. (Sunnaas Rehabilitation Hospital HT)
Ehrlich, Stefan (Universitätsklinikum Carl Gustav Carus an der TU Dresden)
Erk, Susanne (Charité - Universitätsmedizin Berlin)
Espeseth, Thomas (Bjørknes College)
Fatouros-Bergman, Helena (Stockholm Health Care Services)
Fisher, Simon E. (Max Planck Institute for Psycholinguistics)
Fouche, Jean-Paul (University of Cape Town)
Franke, Barbara (Radboud University Medical Center)
Frodl, Thomas (Otto von Guericke University Magdeburg)
Fuentes-Claramonte, Paola (Centro de Investigación Biomédica en Red de Salud Mental)
Glahn, David C. (Boston Children's Hospital (Boston, Estats Units d'Amèrica))
Gotlib, Ian H. (Stanford University)
Grabe, Hans-Jörgen (Site Rostock/Greifswald)
Grimm, Oliver (Goethe Universitat)
Groenewold, Nynke A. (University of Cape Town)
Grotegerd, Dominik (University of Cape Town)
Gruber, Oliver (Heidelberg University)
Gruner, Patricia (VA Connecticut Health System)
Gur, Raquel E (University of Pennsylvania)
Gur, Ruben C. (University of Pennsylvania)
Hahn, Tim (University of Münster)
Harrison, Ben J. (University of Melbourne)
Hartman, Catharina A (University of Groningen)
Hatton, Sean N. (University of Sydney)
Heinz, Andreas (Charité - Universitätsmedizin Berlin)
Heslenfeld, Dirk J. (Vrije Universiteit Amsterdam)
Hibar, Derrek P. (Personalized Healthcare, Genentech, Inc)
Hickie, Ian B. (University of Sydney)
Ho, Beng-Choon (University of Iowa Carver College of Medicine)
Hoekstra, Pieter J. (University Medical Center Groningen, University of Groningen)
Hohmann, Sarah (Heidelberg University)
Holmes, Avram J. (Yale University)
Hoogman, Martine (Radboud University Medical Center)
Hosten, Norbert (University Medicine Greifswald, University of Greifswald)
Howells, Fleur M. (University of Cape Town)
Hulshoff Pol, Hilleke E. (University Medical Center Utrecht)
Huyser, Chaim (De Bascule, Academic Centre for Children and Adolescent Psychiatry)
Jahanshad, Neda (KU Leuven)
James, Anthony (Oxford University)
Jernigan, Terry L. (University of California)
Jiang, Jiyang (University of New South Wales)
Jönsson, Erik G. (Institute of Clinical Medicine, University of Oslo)
Joska, John A. (University of Cape Town)
Kahn, Rene (Icahn School of Medicine at Mount Sinai)
Kalnin, Andrew (Ohio State University College of Medicine)
Kanai, Ryota (Araya, Inc)
Klein, Marieke (University of California San Diego)
Klyushnik, Tatyana P. (Russian Academy of Medical Sciences)
Koenders, Laura (Universiteit van Amsterdam)
Koops, Sanne (University Medical Center Utrecht)
Krämer, Bernd (Heidelberg University)
Kuntsi, Jonna (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
Lagopoulos, Jim (Thompson Institute, University of the Sunshine Coast)
Lázaro, Luisa (Hospital Clínic i Provincial de Barcelona)
Lebedeva, Irina (Russian Academy of Medical Sciences)
Lee, Won Hee (Icahn School of Medicine at Mount Sinai)
Lesch, Klaus-Peter (Julius-Maximilians Universität Würzburg)
Lochner, Christine (Stellenbosch University)
Machielsen, Marise W. J. (Universiteit van Amsterdam)
Maingault, Sophie (Université de Bordeaux)
Martin, Nicholas G. (Berghofer Medical Research Institute)
Martínez-Zalacaín, Ignacio (Institut d'Investigació Biomèdica de Bellvitge)
Mataix-Cols, David (Stockholm Health Care Services)
Mazoyer, Bernard (Université de Bordeaux)
McDonald, Colm (National University of Ireland)
McDonald, Brenna C. (Indiana University School of Medicine)
McIntosh, Andrew M.. (University of Edinburgh)
McMahon, Katie L. (Queensland University of Technology)
McPhilemy, Genevieve (National University of Ireland)
Meinert, Susanne (University of Münster)
Menchón, José M. (Institut d'Investigació Biomèdica de Bellvitge)
Medland, Sarah Elizabeth (Berghofer Medical Research Institute)
Meyer-Lindenberg, Andreas (Central Institute of Mental Health, Heidelberg University)
Naaijen, Jilly (Radboud University)
Najt, Pablo (National University of Ireland)
Nakao, Tomohiro (Kyushu University)
Nordvik, Jan E. (CatoSenteret Rehabilitation Hospital)
Nyberg, Lars (Umeå Center for Functional Brain Imaging, Umeå University)
Oosterlaan, Jaap (Amsterdam Universitair Medische Centra (Amsterdam, Països Baixos))
de la Foz, Víctor Ortiz-García (Instituto de Salud Carlos III)
Paloyelis, Yannis (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
Pauli, Paul (University of Würzburg)
Pergola, Giulio (University of Bari Aldo Moro)
Pomarol-Clotet, Edith (Centro de Investigación Biomédica en Red de Salud Mental)
Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau)
Potkin, Steven G. (University of California at Irvine)
Radua, Joaquim (King's College London)
Reif, Andreas (Goethe Universitat)
Rinker, Daniel A. (Institute of Clinical Medicine, University of Oslo)
Roffman, Joshua L. (Massachusetts General Hospital (Boston))
Rosa, Pedro G. P. (Universidade de São Paulo)
Sacchet, Matthew D. (Harvard Medical School)
Sachdev, Perminder S. (University of New South Wales)
Salvador, Raymond (FIDMAG Germanes Hospitalàries)
Sánchez-Juan, Pascual (Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas)
Sarró, Salvador (FIDMAG Germanes Hospitalàries)
Satterthwaite, Theodore D. (University of Pennsylvania)
Saykin, Andrew J. (Indiana University School of Medicine)
Serpa, Mauricio H. (Universidade de São Paulo)
Schmaal, Lianne (The University of Melbourne)
Schnell, Knut (University Medical Center Göttingen)
Schumann, Gunter (King's College London)
Sim, Kang (Institute of Mental Health)
Smoller, Jordan W. (Massachusetts General Hospital (Boston))
Sommer, Iris (University Medical Center Groningen)
Soriano-Mas, Carles (Institut d'Investigació Biomèdica de Bellvitge)
Stein, Dan J. (Stellenbosch University)
Strike, Lachlan (University of Queensland)
Swagerman, Suzanne C. (Vrije Universiteit)
Tamnes, Christian K. (University of Oslo)
Temmingh, Henk S. (University of Cape Town)
Thomopoulos, Sophia I. (University of Southern California)
Tomyshev, Alexander S. (Russian Academy of Medical Sciences)
Tordesillas-Gutiérrez, Diana (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria))
Trollor, Julian N. (University of New South Wales)
Turner, Jessica A. (Georgia State University)
Uhlmann, Anne (University of Cape Town)
van den Heuvel, Odile A. (Vrije Universiteit)
van den Meer, Dennis (Maastricht University)
van der Wee, Nic J. A. (Leiden University Medical Center)
van Haren, Neeltje E. M. (Erasmus University Medical Center)
van 't Ent, Dennis (Vrije Universiteit)
van Erp, Theo G. M. (University of Greifswald)
Veer, Ilya M. (Charité - Universitätsmedizin Berlin)
Veltman, Dick J. (Vrije Universiteit)
Voineskos, Aristotle (University of Toronto)
Völzke, Henry (German Center for Diabetes Research (DZD))
Walter, Henrik (Charité - Universitätsmedizin Berlin)
Walton, Esther (University of Bath)
Wang, Lei (Northwestern University)
Wang, Yang (Medical College of Wisconsin)
Wassink, Thomas H. (The University of Iowa)
Weber, Bernd (University of Bonn)
Wen, Wei (University of New South Wales)
West, John D. (Indiana University School of Medicine)
Westlye, Lars T. (University of Oslo)
Whalley, Heather (University of Edinburgh)
Wierenga, Lara M. (Leiden University)
Wittfeld, Katharina (Site Rostock/Greifswald)
Wolf, Daniel H. (University of Pennsylvania)
Worker, Amanda (University of British Columbia)
Wright, Margaret J. (University of Queensland)
Yang, Kun (Florida State University)
Yoncheva, Yulyia (NYU Langone Health)
Zanetti, Marcus V. (Hospital Sírio-Libanês)
Ziegler, Georg C. (University of Würzburg)
Thompson, Paul M. (University of Southern California)
Dima, Danai (City University of London)
Universitat Autònoma de Barcelona

Fecha:	2021
Resumen:	Delineating the association of age and cortical thickness in healthy individuals is critical given the association of cortical thickness with cognition and behavior. Previous research has shown that robust estimates of the association between age and brain morphometry require large-scale studies. In response, we used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness. We used fractional polynomial (FP) regression to quantify the association between age and cortical thickness, and we computed normalized growth centiles using the parametric Lambda, Mu, and Sigma method. Interindividual variability was estimated using meta-analysis and one-way analysis of variance. For most regions, their highest cortical thickness value was observed in childhood. Age and cortical thickness showed a negative association; the slope was steeper up to the third decade of life and more gradual thereafter; notable exceptions to this general pattern were entorhinal, temporopolar, and anterior cingulate cortices. Interindividual variability was largest in temporal and frontal regions across the lifespan. Age and its FP combinations explained up to 59% variance in cortical thickness. These results may form the basis of further investigation on normative deviation in cortical thickness and its significance for behavioral and cognitive outcomes. We used cross-sectional data from 17,075 individuals aged 3-90 years from the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) Consortium to infer age-related changes in cortical thickness.
Ayudas:	European Commission 278948 European Commission 602450 European Commission 603016 European Commission 602805 European Commission 667302 European Commission 643051 Instituto de Salud Carlos III PI14/00918 Instituto de Salud Carlos III PI14/00639 Instituto de Salud Carlos III PI060507 Instituto de Salud Carlos III PI050427 Instituto de Salud Carlos III PI020499
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Aging ; Cortical thickness ; Development ; Trajectories
Publicado en:	Human Brain Mapping, Vol. 43 (february 2021) , p. 431-451, ISSN 1065-9471

DOI: 10.1002/hbm.25364
PMID: 33595143

21 p, 3.2 MB

El registro aparece en las colecciones:
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Institut de Recerca Sant Pau
Artículos > Artículos de investigación
Artículos > Artículos publicados