Limited Liver or Lung Colorectal Cancer Metastases. Systemic Treatment, Surgery, Ablation or SBRT
Molla, Meritxell (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Fernandez-Plana, Julen (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya))
Albiol, Santiago (Hospital Clínic i Provincial de Barcelona)
Fondevila, Constantino (Hospital Clínic i Provincial de Barcelona)
Vollmer, Ivan (Hospital Clínic i Provincial de Barcelona)
Cases, Carla (Hospital Clínic i Provincial de Barcelona)
García-Criado, A. (Hospital Clínic i Provincial de Barcelona)
Capdevila Castillón, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Conill, Carles (Hospital Clínic i Provincial de Barcelona)
Fundora, Yliam (Hospital Clínic i Provincial de Barcelona)
Fernández-Martos, Carlos (Instituto Valenciano Oncologia)
Pineda, Estela (Hospital Clínic i Provincial de Barcelona)
Universitat Autònoma de Barcelona

Data:	2021
Resum:	The prognosis for oligometastatic colorectal cancer has improved in recent years, mostly because of recent advances in new techniques and approaches to the treatment of oligometastases, including new surgical procedures, better systemic treatments, percutaneous ablation, and stereotactic body radiation therapy (SBRT). There are several factors to consider when deciding on the better approach for each patient: tumor factors (metachronous or synchronous metastases, RAS mutation, BRAF mutation, disease-free interval, size and number of metastases), patient factors (age, frailty, comorbidities, patient preferences), and physicians' factors (local expertise). These advances have presented major challenges and opportunities for oncologic multidisciplinary teams to treat patients with limited liver and lung metastases from colorectal cancer with a curative intention. In this review, we describe the different treatment options in patients with limited liver and lung metastases from colorectal cancer, and the possible combination of three approaches: systemic treatment, surgery, and local ablative treatments.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Oligometastasis ; Colorectal cancer ; Ablation ; Stereotactic body radiation therapy ; Liver metastases ; Lung metastases
Publicat a:	Journal of clinical medicine, Vol. 10 (may 2021) , ISSN 2077-0383

DOI: 10.3390/jcm10102131
PMID: 34069240

16 p, 3.2 MB

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