Cyclodextrins as capture agents of lipophilic marine toxins
Wirén, Charlotta
Campàs i Homs, Mònica, dir.
Roig, Artur Xavier, dir.
Universitat Autònoma de Barcelona. Facultat de Veterinària

Fecha: 2020
Descripción: 19 pag.
Resumen: Seafood contamination with marine toxins due to harmful algal blooms (HABs) is a global public health issue on the rise. Most countries have monitoring programs for the detection of toxins in shellfish of toxic phytoplankton in seawater to prevent consumer intoxications. The use of solid phase adsorbent and toxin tracking (SPATT) technology as toxin detection straight from the aquatic environment could complement the labourintensive traditional monitoring methods. In this work, several types of cyclodextrins (cyclic oligomers with a conical structure and an internal cavity) have been evaluated as novel materials for SPATT. Cyclodextrins were tested at Masnou harbour (Catalonia, NW Mediterranean) during a Dinophysis sp. bloom. The cyclodextrins and the commercial Diaion (HP-20) were deployed twice for a 1-week period at five different locations of Masnou harbour. At the time of the experiment, Dinophysis sp. reached abundances as high as 91 341 cells /L. Successful accumulations of the lipophilic marine toxins okadaic acid (OA) and pectenotoxin-2 (PTX2) were quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Higher levels of PTX2 were found in all cyclodextrins whereas OA and PTX2 contents were similar in the commercial resin. Accumulation of OA was higher in the commercial resin than in cyclodextrins, but these last proved best for PTX2 adsorption. A clear correlation between cell abundance and toxin accumulation was observed.
Nota: TFM
Nota: One Health
Derechos: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan aquestes es distribueixin sota la mateixa llicència que regula l'obra original i es reconegui l'autoria de l'obra original. Creative Commons
Lengua: Anglès
Titulación: Zoonosi i Una Sola Salut (One Health) [4315915]
Plan de estudios: Màster Universitari en Zoonosi i Una Sola Salut (One Health) [1460]
Documento: Treball de fi de postgrau
Área temática: Veterinària
Materia: Microbiologia dels aliments ; Intoxicació alimentària ; Contaminació dels aliments



19 p, 1.8 MB

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