Standardized comparison of cardiovascular risk factors prevalence in spanish women and men living with hiv and in the general population
Camps-Vilaró, Anna (Institut Hospital del Mar d'Investigacions Mèdiques)
Pérez-Fernández, Silvia (Institut Hospital del Mar d'Investigacions Mèdiques)
Subirana, Isaac (Institut Hospital del Mar d'Investigacions Mèdiques)
Teira, R. (Hospital Sierrallana)
Estrada, V. (Hospital Clínico San Carlos (Madrid))
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau)
Degano, Irene R (Universitat de Vic - Universitat Central de Catalunya)
Marrugat, Jaume 1954- (Institut Hospital del Mar d'Investigacions Mèdiques)
Universitat Autònoma de Barcelona

Date:	2021
Abstract:	People living with HIV (PLWH) have an increased risk of cardiovascular (CV) disease, likely due to a higher prevalence of CV risk factors. We compared the age-standardized prevalence and management of CV risk factors in PLWH to that of the general population in Spain. Blood pressure, lipid, glucose, and anthropometric profiles were cross-sectionally compared along with the treatment of hypertension, dyslipidemia, and diabetes in a general population cohort and a PLWH cohort. Prevalence rates were standardized by the direct method by 10-year age groups in European standard populations and stratified by gender. We included 47,593 individuals aged 35 to 74 years, 28,360 from the general population cohort and 19,233 from the PLWH cohort. Compared to the general population, PLWH had a higher concentration of triglycerides (>35 mg/dL in women and >26 mg/dL in men) and a higher prevalence of smoking (>23% and >17%) and diabetes (>9. 9% and >8. 5%). The prevalence of treated diabetes, hypertension, and dyslipidemia were up to three-fold lower in both women and men living with HIV. There was a significant difference in PLWH compared to the general population in the lipid, glucose, and anthropometric profile. In addition, PLWH were less often treated for diagnosed diabetes, hypertension, and dyslipidemia.
Grants:	Ministerio de Ciencia e Innovación CB16-11-00229 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017SGR222 Instituto de Salud Carlos III PI18-00030 Instituto de Salud Carlos III PI17-00498 Instituto de Salud Carlos III PI14-0700 Instituto de Salud Carlos III PI14-0063 Instituto de Salud Carlos III INT19-00036 Agència de Gestió d'Ajuts Universitaris i de Recerca SLT006-17-00029
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	HIV ; People living with HIV ; Prevalence ; Cardiovascular risk factor ; General population
Published in:	Journal of personalized medicine, Vol. 11 Núm. 11 (november 2021) , p. 1085, ISSN 2075-4426

DOI: 10.3390/jpm11111085
PMID: 34834438

9 p, 265.1 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles