Past Connectivity but Recent Inbreeding in Cross River Gorillas Determined Using Whole Genomes from Single Hairs
Alvarez-Estape, Marina (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Pawar, Harvinder (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Fontsere, Claudia (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Trujillo, Amber (New York University. Department of Anthropology)
Gunson, Jessica L. (New York University. Department of Anthropology)
Bergl, Richard A. (North Carolina Zoo)
Bermejo, Magdalena (Universitat de Barcelona. Departament d'Ecologia i Ciències Ambientals)
Linder, Joshua M. (James Madison University. Department of Anthropology)
McFarland, Kelley (Triton College)
Oates, John F. (City University of New York. Department of Anthropology)
Sunderland-Groves, Jacqueline L. (University of British Columbia . Department of Forest Resources Management)
Orkin, Joseph (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Higham, James P. (New York University. Department of Anthropology)
Viaud-Martinez, Karine A. (Illumina Laboratory Services)
Lizano, Esther (Institut Català de Paleontologia Miquel Crusafont)
Marquès i Bonet, Tomàs 1975- (Institut Català de Paleontologia Miquel Crusafont)

Date:	2023
Abstract:	The critically endangered western gorillas (Gorilla gorilla) are divided into two subspecies: the western lowland (G. g. gorilla) and the Cross River (G. g. diehli) gorilla. Given the difficulty in sampling wild great ape populations and the small estimated size of the Cross River gorilla population, only one whole genome of a Cross River gorilla has been sequenced to date, hindering the study of this subspecies at the population level. In this study, we expand the number of whole genomes available for wild western gorillas, generating 41 new genomes (25 belonging to Cross River gorillas) using single shed hairs collected from gorilla nests. By combining these genomes with publicly available wild gorilla genomes, we confirm that Cross River gorillas form three population clusters. We also found little variation in genome-wide heterozygosity among them. Our analyses reveal long runs of homozygosity (.
Grants:	Agència de Gestió d'Ajuts Universitaris i de Recerca 2018/FI_B100131 Agencia Estatal de Investigación CEX2018-000792-M European Commission 864203 Ministerio de Ciencia e Innovación PID2021-126004NB-100 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00177 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/BP-00265 European Commission 847648
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Non-invasive ; Hairs ; Inbreeding ; Bottleneck ; Gene flow ; Wild gorillas ; NGS ; Cross River gorilla
Published in:	Genes, Vol. 14, Issue 3 (March 2023) , art. 743, ISSN 2073-4425

DOI: 10.3390/genes14030743
PMID: 36981014

15 p, 1.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Institut Català de Paleontologia Miquel Crusafont (ICP)
Articles > Research articles
Articles > Published articles