Influence of the EULAR recommendations for the use of imaging in large vessel vasculitis in the diagnosis of giant cell arteritis : results of the ARTESER register
De Miguel, Eugenio (Hospital Universitario La Paz (Madrid))
Sanchez-Costa, Jesús T. (Reumatología. Unidad de Investigación (Madrid))
Estrada, Paula (Hospital de Sant Joan Despí Moisès Broggi)
Muñoz, Alejandro (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia))
Valero Martínez, Cristina (Hospital Universitario de la Princesa. Servicio de Reumatología)
Moya, Patricia (Institut d'Investigació Biomèdica Sant Pau)
García-Villanueva, María Jesús (Hospital Universitario Ramón y Cajal (Madrid))
Navarro Angeles, Vanessa A. (Hospital de Sant Joan Despí Moisès Broggi)
Lencastre Da Veiga, Carlos Galisteo (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Riveros Frutos, Anne (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Román Ivorra, Jose A. (Hospital Universitari i Politècnic La Fe (València))
Labrada Arrabal, Selena (Hospital del Mar (Barcelona, Catalunya))
Vasques Rocha, Margarida (Hospital Universitario Araba. Servicio de Reumatología)
Iñiguez, Carlota L. (Hospital Universitario Lucus Augusti (Lugo))
García-Gonzalez, María (Hospital Universitario de Canarias (La Laguna))
Molina-Almeda, Clara (Consorci Hospital General Universitari de València. Reumatologia)
Alcalde Villar, María (Hospital Universitario Severo Ochoa. Servicio de Reumatologia)
Mas, Antonio Juan (Hospital Universitari Son Llàtzer (Palma de Mallorca, Balears))
Gonzalez-Gay, MA (Instituto de Investigación Marqués de Valdecilla)
Blanco, Ricardo (Instituto de Investigación Marqués de Valdecilla)

Date:	2022
Abstract:	Objective The main study objective was to determine how giant cell arteritis (GCA) is diagnosed in our clinical practice and whether the EULAR recommendations have influenced the diagnostic procedures used. Methods ARTEritis of the Rheumatology Spanish Society -Sociedad Española de Reumatología (ARTESER) is a multicentre observational retrospective study conducted in 26 hospitals with support from the Spanish Society of Rheumatology. All patients diagnosed with GCA between 1 June 2013 and 29 March 2019 were included. The gold standard for the diagnosis of GCA was the judgement of the physician in charge, according to clinical criteria, supported by data available from laboratory tests, imaging studies (ultrasound, positron emission tomography (PET) and MRI/CT angiography) and temporal artery biopsy (TAB) when available. Results We included 1675 patients with GCA (mean age±SD (76. 9±8. 1) years, 1178 women (70. 3%)). Of these, 776 patients had a positive TAB (46. 3%), 503 (30. 0%) positive ultrasound, 245 positive PET (14. 6%) and 64 positive MRI/CT angiography (3. 8%). These percentages changed substantially over the study. From 2013 to 2019, the use of ultrasound in diagnosis grew from 25. 8% to 52. 9% and PET from 12. 3% to 19. 6%, while use of TAB decreased from 50. 3% to 33. 3%. Conclusions Biopsy was the most widely used diagnostic test for confirming GCA, but use of imaging as a diagnostic tool has grown in recent years. Following publication of the 2018 EULAR recommendations, ultrasound has displaced biopsy as the first-line diagnostic test; TAB was performed in a third and PET in a fifth of cases.
Note:	Altres ajuts: Roche.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	RMD Open, Vol. 8 Núm. 2 (may 2022) , p. e002507, ISSN 2056-5933

DOI: 10.1136/rmdopen-2022-002507
PMID: 36597988

6 p, 577.0 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles