Clinical Impact of Electronic Monitoring Devices of Inhalers in Adults with Asthma or COPD: A Systematic Review and Meta-Analysis
Garin, Noe (Institut d'Investigació Biomèdica Sant Pau)
Zarate-Tamames, Borja (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Gras-Martin, Laura (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Milà, Raimon (Universitat Ramon Llull)
Crespo Lessmann, Astrid (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya))
Curto Sánchez, Elena (Institut d'Investigació Biomèdica Sant Pau)
Hernández Hernández, Marta (Universitat Ramon Llull)
Mestres, Concepció (Universitat Ramon Llull)
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau)
Universitat Autònoma de Barcelona

Date:	2023
Abstract:	We conducted a systematic review and meta-analysis to gain insight into the characteristics and clinical impact of electronic monitoring devices of inhalers (EMDs) and their clinical interventions in adult patients with asthma or COPD. The search included PubMed, Web of Science, Cochrane, Scopus and Embase databases, as well as official EMDs websites. We found eight observational studies and ten clinical trials, assessing a wide range of clinical outcomes. Results from the meta-analysis on adherence to inhalers in a period over three months were favourable in the EMD group (fixed effects model: SMD: 0. 36 [0. 25-0. 48]; random effects model SMD: 0. 41 [0. 22-0. 60]). An exploratory meta-analysis found an improvement in ACT score (fixed effect model SMD: 0. 25 [0. 11-0. 39]; random effects model: SMD: 0. 47 [-0. 14-1. 08]). Other clinical outcomes showed mixed results in the descriptive analyses. The findings of this review highlight the benefits of EMDs in the optimization of adherence to inhaled therapy as well as the potential interest in other clinical outcomes.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Asthma ; Clinical outcomes ; COPD ; Electronic monitoring device ; Meta-analysis ; Medication adherence
Published in:	Pharmaceuticals, Vol. 16 (march 2023) , ISSN 1424-8247

DOI: 10.3390/ph16030414
PMID: 36986513

25 p, 3.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles