Epidemiology of atopic dermatitis in adults : Results from an international survey
Barbarot, Sebastien (CHU de Nantes)
Auziere, Sébastien (Kantar Health)
Gadkari, Abhijit (Regeneron)
Girolomoni, Giampiero (University of Verona)
Puig Sanz, Lluís (Institut d'Investigació Biomèdica Sant Pau)
Simpson, Eric L. (Oregon Health & Science University)
Margolis, David J. (University of Pennsylvania Perelman School of Medicine)
de Bruin-Weller, Marjolein (University Medical Center Utrecht)
Eckert, Laurent (Sanofi)
Universitat Autònoma de Barcelona

Date:	2018
Abstract:	There are gaps in our knowledge of the prevalence of adult atopic dermatitis (AD). To estimate the prevalence of AD in adults and by disease severity. Methods: This international, cross-sectional, web-based survey was performed in the United States, Canada, France, Germany, Italy, Spain, United Kingdom, and Japan. Adult members of online respondent panels were sent a questionnaire for AD identification and severity assessment; demographic quotas ensured population representativeness for each country. A diagnosis of AD required subjects to be positive on the modified UK Working Party/ISAAC criteria and self-report of ever having an AD diagnosis by a physician. The proportion of subjects with AD who reported being treated for their condition was determined and also used to estimate prevalence. Severity scales were Patient-Oriented SCORAD, Patient-Orientated Eczema Measure, and Patient Global Assessment. Among participants by region, the point prevalence of adult AD in the overall/treated populations was 4. 9%/3. 9% in the US, 3. 5%/2. 6% in Canada, 4. 4%/3. 5% in the EU, and 2. 1%/1. 5% in Japan. The prevalence was generally lower for males vs females, and decreased with age. Regional variability was observed within countries. Severity varied by scale and region; however, regardless of the scale or region, proportion of subjects reporting severe disease was lower than mild or moderate disease. Prevalence of adult AD ranged from 2. 1% to 4. 9% across countries. Severe AD represented a small proportion of the overall AD population regardless of measure or region.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Atopic dermatitis ; Epidemiology ; Prevalence ; Severity
Published in:	Allergy, Vol. 73 Núm. 6 (june 2018) , p. 1284-1293, ISSN 1398-9995

DOI: 10.1111/all.13401
PMID: 29319189

10 p, 1.7 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles