Lactic Acid from CO2 : A Carbon Capture and Utilization Strategy Based on a Biocatalytic Approach
Carceller, Albert (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Guillén, Marina (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Álvaro, Gregorio (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)

Data:	2023
Resum:	The EU low-carbon economy aims to reduce the level of CO emission in the EU to 80% by 2050. High efforts are required to achieve this goal, where successful CCU (Carbon Capture and Utilization) technologies will have a high impact. Biocatalysts offer a greener alternative to chemical catalysts for the development of CCU strategies since biocatalysis conforms 10 of the 12 principles of green chemistry. In this study, a multienzymatic system, based on alcohol dehydrogenase (ADH), pyruvate decarboxylase (PDC), and lactate dehydrogenase (LDH), that converts CO and ethanol into lactic acid leading to a 100% atom economy was studied. The system allows cofactor regeneration, thus reducing the process cost. Through reaction media engineering and enzyme ratio study, the performance of the system was able to produce up to 250 μM of lactic acid under the best conditions using 100% CO, corresponding to the highest concentration of lactic acid obtained up to date using this multienzymatic approach. For the first time, the feasibility of the system to be applied under a real industrial environment has been tested using synthetic gas mimicking real blast furnace off-gases composition from the iron and steel industry. Under these conditions, the system was also capable of producing lactic acid, reaching 62 μM. The use of CO as a feedstock for the synthesis of chemicals can contribute to carbon recycling, with a consequent reduction of fossil fuel needs while reducing greenhouse gas emissions. This study reports a biocatalytic CCU strategy to produce lactic acid.
Ajuts:	European Commission 761042 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1462 Agència de Gestió d'Ajuts Universitaris i de Recerca 2019FI_B00139
Nota:	Altres ajuts: Programa Talent UAB-Banc de Santander
Nota:	Altres ajuts: acords transformatius de la UAB
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Multienzymatic systems ; Carbon capture and utilization ; Biocatalysis ; Carbon dioxide
Publicat a:	Environmental Science & Technology, Vol. 57, Issue 51 (December 2023) , p. 21727-21735, ISSN 1520-5851

DOI: 10.1021/acs.est.3c05455
PMID: 38078668

9 p, 3.8 MB

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