Non-Contact Intracardiac Potential Mapping Using Mesh-Based and Meshless Inverse Solvers
Meng, Shu (Auckland Bioengineering Institute. University of Auckland (Nova Zelanda))
Chamorro Servent, Judit (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
Sunderland, Nicholas (University of Bristol (Regne Unit))
Zhao, Jichao (University of Auckland (Nova Zelanda))
Bear, Laura (Centre de Recherche Cardio-Thoracique de Bordeaux (França))
Lever, Nigel A. (University of Auckland (Nova Zelanda))
Sands, Gregory B. (University of Auckland (Nova Zelanda))
LeGrice, Ian John (University of Auckland (Nova Zelanda))
Gillis, Anne M. (Calgary University (Canadà))
Budgett, David M. (University of Auckland (Nova Zelanda))
Smaill, Bruce Henry (University of Auckland (Nova Zelanda))

Data:	2022
Resum:	Atrial fibrillation (AF) is the most common cardiac dysrhythmia and percutaneous catheter ablation is widely used to treat it. Panoramic mapping with multi-electrode catheters has been used to identify ablation targets in persistent AF but is limited by poor contact and inadequate coverage of the left atrial cavity. In this paper, we investigate the accuracy with which atrial endocardial surface potentials can be reconstructed from electrograms recorded with non-contact catheters. An in-silico approach was employed in which "ground-truth" surface potentials from experimental contact mapping studies and computer models were compared with inverse potential maps constructed by sampling the corresponding intracardiac field using virtual basket catheters. We demonstrate that it is possible to 1) specify the mixed boundary conditions required for mesh-based formulations of the potential inverse problem fully, and 2) reconstruct accurate inverse potential maps from recordings made with appropriately designed catheters. Accuracy improved when catheter dimensions were increased but was relatively stable when the catheter occupied >30% of atrial cavity volume. Independent of this, the capacity of non-contact catheters to resolve the complex atrial potential fields seen in reentrant atrial arrhythmia depended on the spatial distribution of electrodes on the surface bounding the catheter. Finally, we have shown that reliable inverse potential mapping is possible in near real-time with meshless methods that use the Method of Fundamental Solutions.
Drets:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Llengua:	Anglès
Document:	Article ; recerca ; Versió publicada
Matèria:	Atrial fibrillation ; Endocardial potentials ; Inverse problem ; Non-contact mapping ; Open basket catheters
Publicat a:	Frontiers in physiology, Vol. 13 (july 2022) , p. 873630, ISSN 1664-042X

DOI: 10.3389/fphys.2022.873630
PMID: 35874529

12 p, 2.0 MB

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