Population structure and identification of genomic regions associated with productive traits in five Italian beef cattle breeds
Colombi, Daniele (University of Perugia. Department of Agricultural, Food and Environmental Sciences)
Rovelli, Giacomo (Centre de Recerca en Agrigenòmica)
Luigi Sierra, Maria Gracia (Centre de Recerca en Agrigenòmica)
Ceccobelli, Simone (Università Politecnica delle Marche. Department of Agricultural, Food and Environmental Sciences)
Guan, Dailu (Centre de Recerca en Agrigenòmica)
Perini, Francesco (University of Padova. Department of Agronomy, Food, Natural Resources, Animals and Environment)
Sbarra, Fiorella (National Association of Italian Beef-Cattle Breeders)
Quaglia, Andrea (National Association of Italian Beef-Cattle Breeders)
Sarti, Francesca Maria (University of Perugia. Department of Agricultural, Food and Environmental Sciences)
Pasquini, Marina (Università Politecnica delle Marche. Department of Agricultural, Food and Environmental Sciences)
Amills i Eras, Marcel (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments)
Lasagna, Emiliano (University of Perugia. Department of Agricultural, Food and Environmental Sciences)

Date:	2024
Abstract:	Italy has a long history in beef production, with local breeds such as Marchigiana, Chianina, Romagnola, Maremmana, and Podolica which produce high-quality meat. Selection has improved meat production, precocity, growth ability and muscle development, but the genetic determinism of such traits is mostly unknown. Using 33K SNPs-data from young bulls (N = 4064) belonging to these five Italian breeds, we demonstrated that the Maremmana and Podolica rustic breeds are closely related, while the specialised Marchigiana, Chianina, and Romagnola breeds are more differentiated. A genome-wide association study for growth and muscle development traits (average daily gain during the performance test, weight at 1 year old, muscularity) was conducted in the five Italian breeds. Results indicated a region on chromosome 2, containing the myostatin gene (MSTN), which displayed significant genome-wide associations with muscularity in Marchigiana cattle, a breed in which the muscle hypertrophy phenotype is segregating. Moreover, a significant SNP on chromosome 14 was associated, in the Chianina breed, to muscularity. The identification of diverse genomic regions associated with conformation traits might increase our knowledge about the genomic basis of such traits in Italian beef cattle and, eventually, such information could be used to implement marker-assisted selection of young bulls tested in the performance test.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Animal breeding ; Genetic association study ; Genetic markers ; Genomics
Published in:	Scientific reports, Vol. 14 (April 2024) , art. 8529, ISSN 2045-2322

DOI: 10.1038/s41598-024-59269-z
PMID: 38609445

10 p, 2.2 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > CRAG (Centre for Research in Agricultural Genomics)
Articles > Research articles
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