SEOM-GEIS clinical guideline for gastrointestinal stromal tumors (2022)
Serrano, Cesar (Hospital Universitari Vall d'Hebron)
Álvarez, Rosa (Hospital General Universitario Gregorio Marañón)
Carrasco, Juan Antonio (Hospital Álvaro Cunqueiro (Vigo))
Marquina, Gloria (Hospital Universitario Clínico San Carlos (Madrid))
Martínez-García, Jerónimo (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia))
Martínez-Marín, Virginia (Hospital Universitario La Paz (Madrid))
Sala, María Ángeles (Hospital Universitario de Basurto (Bilbao, Biscaia))
Sebio, Ana (Institut d'Investigació Biomèdica Sant Pau)
Sevilla, Isabel (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia))
Martín-Broto, Javier (Hospital Universitario Fundación Jiménez Díaz)
Universitat Autònoma de Barcelona

Date:	2023
Abstract:	Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin, and a paradigmatic model for a successful rational development of targeted therapies in cancer. The introduction of tyrosine kinase inhibitors with activity against KIT/PDGFRA in both localized and advanced stages has remarkably improved the survival in a disease formerly deemed resistant to all systemic therapies. These guidelines are elaborated by the conjoint effort of the Spanish Society of Medical Oncology (SEOM) and the Spanish Sarcoma Research Group (GEIS) and provide a multidisciplinary and updated consensus for the diagnosis and treatment of GIST patients. We strongly encourage that the managing of these patients should be performed within multidisciplinary teams in reference centers.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Avapritinib ; GIST ; Imatinib ; Ripretinib
Published in:	Clinical & translational oncology, Vol. 25 Núm. 9 (september 2023) , p. 2707-2717, ISSN 1699-3055

DOI: 10.1007/s12094-023-03177-7
PMID: 37129716

11 p, 1.0 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles