Cardiometabolic health in people with HIV : expert consensus review
Batterham, Rachel L. (University College London Hospitals Biomedical Research Centre)
Bedimo, Roger J. (University of Texas Southwestern Medical Center)
Diaz, Ricardo S. (Universidade Federal de São Paulo)
Guaraldi, Giovanni (University of Modena and Reggio Emilia (Itàlia))
Lo, Janet (Massachusetts General Hospital (Boston))
Martínez, Esteban (Universitat de Barcelona)
McComsey, Grace A. (Case Western Reserve University (Estats Units d'Amèrica))
Milinkovic, Ana (Imperial College London)
Naito, Toshio (Juntendo University Faculty of Medicine (Tokio, Japò))
Noe, Sebastian (MVZ Karlsplatz (Munich, Alemanya))
O'Shea, Donak (University College Dublin School of Medicine)
Paredes, Roger (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Schapiro, Jonathan M. (Sheba Medical Center (Tel Aviv, Israel))
Sulkowski, Mark S. (Johns Hopkins University School of Medicine)
Venter, François (University of the Witwatersrand (Johannesburg, South Africa))
Waters, Laura (Central and North West London NHS Foundation Trust (Regne Unit))
Yoruk, Ilksen Ungan (General Medicines Europe (Middlesex, Regne Unit))
Young, Benjamin (ViiV Healthcare (Estats Units d'Amèrica))

Date:	2024
Abstract:	Objectives: To develop consensus data statements and clinical recommendations to provide guidance for improving cardiometabolic health outcomes in people with HIV based on the knowledge and experience of an international panel of experts. Methods: A targeted literature review including 281 conference presentations, peer-reviewed articles, and background references on cardiometabolic health in adults with HIV published between January 2016 and April 2022 was conducted and used to develop draft consensus data statements. Using a modified Delphi method, an international panel of 16 experts convened in workshops and completed surveys to refine consensus data statements and generate clinical recommendations. Results: Overall, 10 data statements, five data gaps and 14 clinical recommendations achieved consensus. In the data statements, the panel describes increased risk of cardiometabolic health concerns in people with HIV compared with the general population, known risk factors, and the potential impact of antiretroviral therapy. The panel also identified data gaps to inform future research in people with HIV. Finally, in the clinical recommendations, the panel emphasizes the need for a holistic approach to comprehensive care that includes regular assessment of cardiometabolic health, access to cardiometabolic health services, counselling on potential changes in weight after initiating or switching antiretroviral therapy and encouraging a healthy lifestyle to lower cardiometabolic health risk. Conclusions: On the basis of available data and expert consensus, an international panel developed clinical recommendations to address the increased risk of cardiometabolic disorders in people with HIV to ensure appropriate cardiometabolic health management for this population.
Note:	This work was supported by ViiV Healthcare. Editorial assistance was funded by ViiV Healthcare.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Ressenya ; recerca ; Versió publicada
Subject:	Cardiometabolic Risk Factors ; Cardiovascular Diseases ; Consensus ; Delphi Technique ; HIV Infections ; Humans ; Risk Factors
Published in:	Journal of antimicrobial chemotherapy, Vol. 79 Núm. 6 (january 2024) , p. 1218-1233, ISSN 1460-2091

DOI: 10.1093/jac/dkae116
PMID: 38656584

16 p, 689.3 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
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Articles > Published articles
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