Plasmonic biosensors : Towards fully operative detection platforms for biomedical application and its potential for the diagnosis of autoimmune diseases
Giarola, Juliana Fatima (Institut Català de Nanociència i Nanotecnologia)
Estévez, M. Carmen (Institut Català de Nanociència i Nanotecnologia)
Lechuga, Laura M. (Institut Català de Nanociència i Nanotecnologia)

Date:	2024
Abstract:	In-vitro diagnostics (IVD) has become an in-demand area with a high-achievement transformation due to the expansion of new technologies. Technology has grown from time-consuming laboratory techniques to modern automated immunoassays and progressed with real-time sensing through the emergence of biosensor devices. Plasmonic biosensors are one of the most employed optical biosensors and stand out for their versatility and wide range of applications in diagnostic tests. One of the clinical diagnostics areas of growing interest is autoimmune diseases (AD), which have been increasingly prevalent worldwide. There is a rising demand for reliable and early AD diagnosis tools. This review highlights the main challenges for early AD diagnostics and the advanced plasmonic biosensors that have been exploited for AD biomarker detection, including brief descriptions of their analytical performance. Finally, the prospects and trends in this area are outlined, thinking about developing multiplexed platforms capable of addressing the multianalyte nature of one disease.
Grants:	Agencia Estatal de Investigación PDC2021-121325-I00 Agencia Estatal de Investigación CEX2021-001214-S Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00456
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Surface plasmon resonance ; Biosensor ; Optical devices ; Autoantibodies ; Autoimmune disease ; Diagnosis
Published in:	TrAC - Trends in Analytical Chemistry, Vol. 176 (July 2024) , art. 117763, ISSN 1879-3142

DOI: 10.1016/j.trac.2024.117763

14 p, 4.0 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles