Web of Science: 1 cites, Scopus: 1 cites, Google Scholar: cites,
Supporting legislative action : Urinary levels of phthalates and phenols among influencers in the 'Plastics in the spotlight' advocacy initiative
Pumarega, José Antonio (Institut Hospital del Mar d'Investigacions Mèdiques)
Buscà, Oriol (Institut Hospital del Mar d'Investigacions Mèdiques)
Gasull, Magda (Institut Hospital del Mar d'Investigacions Mèdiques)
Porta, Miquel 1957- (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i Medicina Preventiva i Salut Pública)

Data: 2023
Resum: Background: Society-wide initiatives to prevent human exposure to plastic residues include laws and policies. Such measures require citizens' support, which can be increased by honest advocacy and pedagogic projects. These efforts must have a scientific basis. Objective: To assist the 'Plastics in the spotlight' advocacy initiative raise awareness among the general public of the presence of plastic residues in the human body, and to increase citizens' support for legislation on plastic control in the European Union. Methods: Spot urine samples of 69 volunteers with cultural and political influence from Spain, Portugal, Latvia, Slovenia, Belgium, and Bulgaria were collected. Concentrations of 30 phthalate metabolites and phenols were determined through a high-performance liquid chromatography with tandem mass spectrometry and ultra-high-performance liquid chromatography with tandem mass spectrometry, respectively. Results: At least 18 compounds were detected in all urine samples. The maximum number of compounds detected per participant was 23, and the mean, 20. 5. Phthalates were detected more frequently than phenols. Median concentrations were highest for monoethyl phthalate (41. 6 ng/mL, adjusted for specific gravity), and maximum concentrations were highest for mono-iso-butyl phthalate (1345. 1 ng/mL), oxybenzone (1915. 1 ng/mL), and triclosan (949. 6 ng/mL). Most reference values were not exceeded. Women had higher concentrations of the 14 phthalate metabolites and oxybenzone than men. Urinary concentrations were not correlated with age. Discussion: The study had three main limitations: method of subject selection (volunteers), small sample size, and limited data on determinants of exposure. Studies on volunteers do not pretend to be representative of the general population and are no substitute for biomonitoring studies in representative samples of the populations of interest. Studies as ours can only illustrate the existence and some aspects of the problem, and can raise awareness among citizens concerned by the evidence that the studies provide in a group of subjects who are humanly appealing. Conclusions: The results illustrate that human exposure to phthalates and phenols is widespread. All countries appeared to be similarly exposed to these contaminants, with higher levels in females. Most concentrations did not exceed reference values. The effects of this study on the objectives of the 'Plastics in the spotlight' advocacy initiative deserve a specific analysis from policy science.
Ajuts: Instituto de Salud Carlos III PI17/00088
Instituto de Salud Carlos III PI21/00052
Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-00439
Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00043
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Llengua: Anglès
Document: Article ; recerca ; Versió acceptada per publicar
Matèria: Environmental pollutants ; Phthalates ; Phenols ; Advocacy
Publicat a: Environmental Research, Vol. 231 (August 2023) , ISSN 1096-0953

DOI: 10.1016/j.envres.2023.116205


Disponible a partir de: 2025-08-31
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