Resting State Electrophysiological Profiles and Their Relationship with Cognitive Performance in Cognitively Unimpaired Older Adults : A Systematic Review
Chino, Brenda (Universitat Autònoma de Barcelona. Institut de Neurociències)
López-Sanz, David (Universidad Complutense de Madrid)
Doval, Sandra (Universidad Complutense de Madrid)
Torres-Simón, Lucía (Universidad Complutense de Madrid)
de Frutos Lucas, Jaisalmer (Universidad Complutense de Madrid)
Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències)
Zegarra-Valdivia, Jonathan (Universidad Señor de Sipán (Chiclayo, Perú))
Maestú, Fernando (Universidad Complutense de Madrid)

Date:	2024
Abstract:	Aging is a complex and natural process. The physiological decline related to aging is accompanied by a slowdown in cognitive processes, which begins shortly after individuals reach maturity. These changes have been sometimes interpreted as a compensatory sign and others as a fingerprint of deterioration. In this context, our aim is to uncover the mechanisms that underlie and support normal cognitive functioning in the brain during the later stages of life. With this purpose, a systematic literature search was conducted using PubMed, Scopus, and Web of Science databases, which identified 781 potential articles. After applying inclusion and exclusion criteria, we selected 12 studies that examined the brain oscillations patterns in resting-state conditions associated with cognitive performance in cognitively unimpaired older adults. Although cognitive healthy aging was characterized differently across studies, and various approaches to analyzing brain activity were employed, our review indicates a relationship between alpha peak frequency (APF) and improved performance in neuropsychological scores among cognitively unimpaired older adults. A higher APF is linked with a higher score in intelligence, executive function, and general cognitive performance, and could be considered an optimal, and easy-to-assess, electrophysiological marker of cognitive health in older adults.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Aging ; Alpha peak frequency ; Alzheimer's disease ; Cognitive performance ; Cognitively unimpaired ; Resting-state ; Systematic review
Published in:	Journal of Alzheimer's disease, Vol. 100 (july 2024) , p. 453-468, ISSN 1875-8908

DOI: 10.3233/JAD-231009
PMID: 38875030

16 p, 322.7 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Neurociències (INc)
Articles > Research articles
Articles > Published articles