Hyperangulated versus Macintosh blades for intubation with videolaryngoscopy in ICU : The randomised multicentre INVIBLADE-ICU trial study protocol
Taboada, Manuel (Hospital of Santiago)
Estany-Gestal, Ana (Fundación Instituto de Investigaciones Sanitarias (FIDIS))
Fernández, Jorge (Hospital of Santiago)
Vazquez, Olalla (Hospital of Santiago)
Pajares, Azucena (Hospital Universitari i Politècnic La Fe (València))
Ramasco, Fernando (Hospital Universitario de la Princesa (Madrid))
Martínez, Sara (Hospital Clínic Universitari (València))
Vallejo, Irene (Hospital Universitario La Paz (Madrid))
Pérez, Ana (Hospital General Universitario de Elche)
Rama-Maceiras, Pablo (University Clinical Hospital)
Bermúdez, María (Hospital Universitario Lucus Augusti (Lugo))
Power, Mercedes (Hospital General Universitario Gregorio Marañón)
García-Álvarez, Raquel (Hospital 12 de Octubre (Madrid))
Fernández-Villa, Inmaculada (Complejo Asistencial Universitario de Leon)
Aguilera, Jose Luis (Hospital Universitario Virgen de las Nieves (Granada))
Carrió, Marta (Hospital de Denia)
Cabadas, Rafael (Hospital Povisa (Vigo, Pontevedra))
Rubín, Anxo (Hospital de Donostia (Sant Sebastià, País Basc))
Williams, Mónica Mercedes (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria))
Fernández-García, Raquel (Hospital Universitario de Móstoles (Madrid))
Becerra-Bolaños, Angel (Hospital Universitario de Gran Canaria Dr. Negrín)
Gine Serven, Marta (Institut de Recerca Sant Pau)
García, Francisco Javier (Complejo Asistencial de Segovia)
Iglesias, María Cristina (Hospital Universitario Central de Asturias)
Santamarina, Rosaura María (Hospital Universitario de Cabueñes (Gijón))
Del Valle, Sara (Puerta de Hierro University Hospital)
Charco, Luisa María (Albacete University Hospital Complex)
Alonso, María Concepción (University Clinical Hospital)
Rodríguez, Inés María (Complexo Hospitalario Universitario de Vigo)
Varela, Marina (Complejo Hospitalario Universitario de Pontevedra)
Hermoso, Jose Ignacio (Hospital Universitario de Cáceres)
Vives, Marc (Clinica Universitaria de Navarra)
Cabaleiro, Teresa (University of Santiago de Compostela (USC))
Universitat Autònoma de Barcelona

Fecha:	2024
Resumen:	Introduction Compared with the operating room, tracheal intubations in the intensive care unit (ICU) are associated with worsened glottic view, decreased first-time success rate and increase in the technical difficulty of intubation and incidence of complications. Videolaryngoscopes (VLs) have been proposed to improve airway management, and while recent studies have confirmed that VLs improve intubation conditions in this patient population, there remains a lack of clarity regarding the selection between a standard Macintosh blade or a hyperangulated one, to determine which yields the best outcomes. The purpose of this study was to compare successful intubation on the first attempt with the Macintosh VL versus the hyperangulated VL during tracheal intubation in ICU patients. We hypothesise that tracheal intubation using the hyperangulated VL will improve the frequency of successful intubation on the first attempt. Methods and analysis The INtubation VIdeolaryngoscopy BLADE-ICU trial is a prospective, multicentre, open-label, interventional, randomised, controlled superiority study conducted in 29 ICUs in Spain. Patients will be randomly assigned in a 1:1 ratio to undergo intubation using a Macintosh VL (control group) or a hyperangulated VL (experimental group) for the first intubation attempt. The primary outcome is successful intubation on the first attempt. The secondary outcomes include the time to intubation, attempts for successful intubation, laryngoscopic vision assessed with the modified Cormack-Lehane scale, the need for adjuvant airway devices for intubation, difficulty assessed by the anaesthesiologist and complications during tracheal intubation. Enrolment began on 1 May 2024 and is expected to be completed in 2025. Ethics and dissemination The study protocol was approved on 29 February 2024, by the Ethics Committee of Galicia (CEImG, code No. 2024-031). The results will be submitted for publication in a peer-reviewed journal.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Adult anaesthesia ; Adult intensive & critical care ; Clinical Trial
Publicado en:	BMJ open, Vol. 14 Núm. 9 (may 2024) , p. e086691, ISSN 2044-6055

DOI: 10.1136/bmjopen-2024-086691
PMID: 39237284

13 p, 382.6 KB

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