Comparable bone penetration between antibiotic-loaded and plain bone cement in total knee arthroplasty
Fontanellas Fes, Albert (Universitat Autònoma de Barcelona)
Hinarejos Gómez, Pedro (Hospital del Mar (Barcelona, Catalunya))
Pérez-Prieto, Daniel (Hospital del Mar (Barcelona, Catalunya))
Martínez-Lozano, Jan (Hospital del Mar (Barcelona, Catalunya))
Sánchez-Soler, Juan (Hospital del Mar (Barcelona, Catalunya))
Torres-Claramunt, Raúl (Hospital del Mar (Barcelona, Catalunya))
Perelli, Simone (Hospital del Mar (Barcelona, Catalunya))
Monllau García, Joan Carles (Hospital del Mar (Barcelona, Catalunya))

Data:	2025
Resum:	Introduction: One of the main concerns around the use of antibiotic-loaded bone cement (ALBC) is the potential reduction in the mechanical properties of the cement when antibiotics are admixed. The purpose of this study was to determine whether there is a difference between plain cement and ALBC in terms of radiological intrusion into the bone in total knee arthroplasties (TKAs). Methods: Prospective randomized study of 80 consecutive patients who underwent TKA. Depending on the cement used, patients were divided into two groups by a computer-generated randomization programme: the cement without antibiotic (Group 1) or the ALBC (Group 2). Cement intrusion was measured in postoperative radiographs in eight different regions in the tibial component and six regions in the femoral component. Results: The average cement intrusion was similar in both groups (p = nonsignificance [n. s. ]). Group 1 (plain cement) had an average cement intrusion in the femur of 1. 4 mm (±0. 4) and 2. 4 mm (±0. 4) in the tibia. In Group 2 (ALBC), the average cement intrusion in the femur came to 1. 6 (±0. 5) and 2. 4 mm (±0. 5) in the tibia. In 80% of the patients, the cement intrusion in the tibia averaged a minimum of 2 mm, being similar in both groups (p = n. s. ). Conclusion: There are no differences in bone intrusion when comparing plain cement to ALBC. Therefore, the use of ALBC in primary TKA may be indicated, achieving optimal bone penetration. Level of Evidence: Level I.
Drets:	Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.
Llengua:	Anglès
Document:	Article ; recerca ; Versió acceptada per publicar
Publicat a:	Knee Surgery, Sports Traumatology, Arthroscopy, Vol. 33, Núm. 1 (january 2025) , p. 364-370, ISSN 1433-7347

DOI: 10.1002/ksa.12379

Postprint 16 p, 374.7 KB

El registre apareix a les col·leccions:
Articles > Articles de recerca
Articles > Articles publicats