Web of Science: 3 citations, Scopus: 3 citations, Google Scholar: citations,
Precision nutrition impact on metabolic health and quality of life in aging population after a 3-month intervention : A randomized intervention
Galarregui, Cristina (Universidad de Navarra)
Navas-Carretero, Santiago (Universidad de Navarra)
Zulet, M. Angeles (Universidad de Navarra)
González-Navarro, Carlos J. (Universidad de Navarra)
Martínez, J. Alfredo (Universidad de Navarra)
de Cuevillas, Begoña (Universidad de Navarra)
Marcos-Pasero, Helena (Nutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute)
Aguilar-Aguilar, Elena (Nutrition and Clinical Trials Unit, GENYAL Platform IMDEA-Food Institute)
Reglero, Guillermo (Institute of Food Science Research (CIAL) CEI UAM+CSIC)
Ramirez de Molina, Ana (IMDEA-Food Institute (Madrid))
Chausa, Paloma (Universidad Politécnica de Madrid)
Iniesta-Chamorro, Jose M. (Universidad Politécnica de Madrid)
Hernando, M.Elena (Universidad Politécnica de Madrid)
Gómez, Emilio (Universidad Politécnica de Madrid)
Garcia-Rudolph, Alejandro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
García-Molina, Alberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Loria-Kohen, Viviana. (GENYAL Platform IMDEA-Food Institute)
Abete, Itziar (Universidad de Navarra)

Date: 2024
Abstract: Objectives: Innovative precision dietary procedures are required to promote healthy aging. This study aimed to evaluate the effects of a personalised strategy based on the inclusion of individualised foods and digital tools on overall health status and quality of life within a follow-up of 3 months in older adults with overweight or obesity. Methods: 127 men and women aged between 50 and 80 years with overweight/obesity participated in the study-between January 2020 and September 2020 at the Center for Nutrition Research-University of Navarra and IMDEA-ALIMENTACIÓN-and were randomly assigned to a usual-care group (standard recommendations) or precision group (precision nutrition strategy based on the inclusion of individualised foods and a mobile application). Anthropometry, body fat percentage, biochemical parameters, diet, and quality of life (SF-36 Health Survey) were assessed at baseline and after 3 months. Results: Both strategies were found to improve overall metabolic health; however, the precision approach demonstrated significantly better outcomes. The precision strategy reduced body weight at 3 months (-4. 3 kg; p < 0. 001) with significant improvements in body fat percentage, blood pressure and general metabolic health (glycated haemoglobin; alanine aminotransferase; aspartate aminotransferase; hepatic steatosis index) in comparison with the standard recommendations. The precision approach significantly enhanced the quality of life (SF-36) of individuals, with additional improvements in emotional well-being (p = 0. 024) and vitality (p = 0. 008). Adherence to the Mediterranean diet was significantly associated with a higher quality of life and vitality. Conclusion: These results support the benefit of precision nutrition approaches for promoting healthy aging and emotional well-being, enhancing the quality of life in aging populations, during the COVID-19 pandemic.
Grants: Ministerio de Educación, Cultura y Deporte FPU17/06330
Note: Altres ajuts: Programa Estratégico CIEN" (IDI-20160734)
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades. Creative Commons
Language: Anglès
Document: Article ; recerca ; Versió publicada
Subject: Precision nutrition ; Healthy aging ; Chronic diseases ; Functional foods ; Quality of life
Published in: The Journal of nutrition, health and aging, Vol. 28 Núm. 7 (July 2024) , ISSN 1760-4788

DOI: 10.1016/j.jnha.2024.100289
PMID: 38865737


9 p, 257.0 KB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut d'Investigació en Ciencies de la Salut Germans Trias i Pujol (IGTP)
Articles > Research articles
Articles > Published articles

 Record created 2025-05-14, last modified 2025-10-12



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