Diagnosed and undiagnosed cough-related stress urinary incontinence in women with refractory or unexplained chronic cough : Its impact on general health status and quality of life
Arismendi, Ebymar (Hospital Clínic i Provincial de Barcelona)
Puente, Luis (Hospital General Universitario Gregorio Marañón)
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Dávila, Ignacio (Universidad de Salamanca)
Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid))
González-Barcala, Francisco-Javier (Universidade de Santiago de Compostela)
Crespo Lessmann, Astrid (Institut de Recerca Sant Pau)
Sánchez-Jareño, Marta (Medical Affairs. MSD)
Rivas-Pardinas, Cristina (Medical Affairs. MSD)
Cea-Calvo, Luis (Medical Affairs. MSD)
Universitat Autònoma de Barcelona

Date:	2024
Abstract:	Background: Stress urinary incontinence (SUI) is common in women with chronic cough but may be overlooked. Objective: To determine the frequency of underdiagnosis of cough-related SUI and its impact on women's general health status and quality of life (QoL). Methods: Data were analyzed for 147 women with refractory/unexplained chronic cough. Relevant details were collected from clinical charts and a patient-completed survey. General health status was assessed using the EuroQoL visual analogue scale (EQ-VAS) and QoL with the cough-specific Leicester Cough Questionnaire (LCQ). Results: Women were classified into diagnosed (n = 32; 21. 8%) or undiagnosed (n = 33; 22. 4%) cough-related SUI, and no SUI (n = 82; 55. 6%) groups. Women with versus without cough-related SUI perceived poorer health status and greater impact of cough on everyday lives. Mean LCQ scores were significantly lower in cough-related SUI groups versus no SUI group. In multivariate analysis, the presence of cough-related SUI was significantly associated with lower EQ-VAS and LCQ scores. Conclusion: In our cohort, 44% of women had cough-related SUI, and half were undiagnosed. Irrespective of diagnosis, impairment to everyday lives and QoL was similar. Diagnosing cough-related SUI may identify additional patients who can benefit from therapies to suppress cough and improve QoL.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Chronic cough ; Spain ; Cough-related quality of life ; Diagnosis ; Stress urinary incontinence ; Survey
Published in:	Chronic Respiratory Disease, Vol. 21 (1-12 2024) , ISSN 1479-9731

DOI: 10.1177/14799731241273751
PMID: 39222070

9 p, 586.8 KB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Parc Taulí Research and Innovation Institute (I3PT
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Health sciences and biosciences > Institut de Recerca Sant Pau
Articles > Research articles
Articles > Published articles